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Database: UniProt
Entry: J7S346_KAZNA
LinkDB: J7S346_KAZNA
Original site: J7S346_KAZNA 
ID   J7S346_KAZNA            Unreviewed;       795 AA.
AC   J7S346;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   31-JUL-2019, entry version 36.
DE   RecName: Full=ATP-grasp domain-containing protein {ECO:0000259|PROSITE:PS50975};
GN   Name=KNAG0B00350 {ECO:0000313|EMBL:CCK68484.1};
GN   OrderedLocusNames=KNAG_0B00350 {ECO:0000313|EMBL:CCK68484.1};
OS   Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 /
OS   CCRC 22969 / KCTC 17520 / NBRC 10181 / NCYC 3082) (Yeast)
OS   (Saccharomyces naganishii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX   NCBI_TaxID=1071383 {ECO:0000313|EMBL:CCK68484.1, ECO:0000313|Proteomes:UP000006310};
RN   [1] {ECO:0000313|EMBL:CCK68484.1, ECO:0000313|Proteomes:UP000006310}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC   / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RX   PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA   Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S.,
RA   Byrne K.P., Wolfe K.H.;
RT   "Evolutionary erosion of yeast sex chromosomes by mating-type
RT   switching accidents.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN   [2] {ECO:0000313|Proteomes:UP000006310}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC   / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RA   Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S.,
RA   Byrne K.P., Wolfe K.H.;
RT   "Genome sequence of Kazachstania naganishii.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; HE978315; CCK68484.1; -; Genomic_DNA.
DR   STRING; 588726.J7S346; -.
DR   EnsemblFungi; CCK68484; CCK68484; KNAG_0B00350.
DR   OMA; LLERHNC; -.
DR   OrthoDB; 105366at2759; -.
DR   Proteomes; UP000006310; Chromosome 2.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EnsemblFungi.
DR   GO; GO:0004641; F:phosphoribosylformylglycinamidine cyclo-ligase activity; IEA:EnsemblFungi.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:EnsemblFungi.
DR   GO; GO:0009113; P:purine nucleobase biosynthetic process; IEA:EnsemblFungi.
DR   CDD; cd02196; PurM; 1.
DR   Gene3D; 3.30.1330.10; -; 1.
DR   Gene3D; 3.30.1490.20; -; 1.
DR   Gene3D; 3.90.600.10; -; 1.
DR   Gene3D; 3.90.650.10; -; 1.
DR   HAMAP; MF_00741; AIRS; 1.
DR   HAMAP; MF_00138; GARS; 1.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR016185; PreATP-grasp_dom_sf.
DR   InterPro; IPR020561; PRibGlycinamid_synth_ATP-grasp.
DR   InterPro; IPR000115; PRibGlycinamide_synth.
DR   InterPro; IPR020560; PRibGlycinamide_synth_C-dom.
DR   InterPro; IPR037123; PRibGlycinamide_synth_C_sf.
DR   InterPro; IPR020559; PRibGlycinamide_synth_CS.
DR   InterPro; IPR020562; PRibGlycinamide_synth_N.
DR   InterPro; IPR010918; PurM-like_C_dom.
DR   InterPro; IPR036676; PurM-like_C_sf.
DR   InterPro; IPR016188; PurM-like_N.
DR   InterPro; IPR036921; PurM-like_N_sf.
DR   InterPro; IPR004733; PurM_cligase.
DR   InterPro; IPR011054; Rudment_hybrid_motif.
DR   PANTHER; PTHR10520; PTHR10520; 1.
DR   Pfam; PF00586; AIRS; 1.
DR   Pfam; PF02769; AIRS_C; 1.
DR   Pfam; PF01071; GARS_A; 1.
DR   Pfam; PF02843; GARS_C; 1.
DR   Pfam; PF02844; GARS_N; 1.
DR   SMART; SM01210; GARS_C; 1.
DR   SUPFAM; SSF51246; SSF51246; 1.
DR   SUPFAM; SSF52440; SSF52440; 1.
DR   SUPFAM; SSF55326; SSF55326; 1.
DR   SUPFAM; SSF56042; SSF56042; 1.
DR   TIGRFAMs; TIGR00877; purD; 1.
DR   TIGRFAMs; TIGR00878; purM; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
DR   PROSITE; PS00184; GARS; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006310};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006310}.
FT   DOMAIN      116    324       ATP-grasp. {ECO:0000259|PROSITE:PS50975}.
SQ   SEQUENCE   795 AA;  84860 MW;  51250589B80D5D7B CRC64;
     MSLNVLVLGN GGREHTLVWK LSQSATVNKV YVAPGNGGTA TMGSAKVENV ANLTPDPSNF
     DALQKFAVEN QIGLVVPGPE QPLVDGITSV FTKVGIPVFG PSAKAAQLEG SKIFSKNFMQ
     RHSIPTARYF SSDSYQDALK HIDSVDYSVV IKADGVAAGK GVLIPTSKEE AHDALKTIMV
     EKQFGDAGDS VVIEEFLEGE EISILTISDG YSHFNLPAAQ DHKRVGENDT GLNTGGMGAY
     APAPVATNAL MTKIDHEIIK PSIDGLRRDR LPFVGVLFTG LIITKDGPKV LEYNVRFGDP
     ETQTVLPLLT DDTDLAQVFL AAAEHRLDSV EIKVKDNYFA TTVVLAAGGY PEAYHKGDEV
     TISKGQLPEN TFVFHAGTAV NGDQKLVSNG GRVIAASAVA PTLREAVDRA YEAVDCIQFN
     NRHFRRDIAH RAFKELESRA KVAITYADSG VSVDAGNLLV QKIKDNVKST KRPGADSDIG
     GFGGVFDLKA AGYDTDDTLL VAATDGVGTK LIIAQETNIH DTVGIDLVAM NVNDLVVQGA
     EPLLFLDYFA TGALDIKIAS DFVSGVVDGC KQSGCALVGG ETSEMPGMYP PGHYDTNGTA
     VGAVKKSDIL PKINEMTAGN VLLGLASDGV HSNGFSLVRK VIKHAGLSWD EPCPWDSTKT
     LGEGILVPTR IYVKQLLPSI NEKLLLGLAH ITGGGLVENI PRAIPSNLQA QVDMNSWEVP
     EVMKWFGKAG NIPVDDILRT LNMGIGMVLI VKKENVSRVK ELLKEANETV YEIGSLVEKP
     EGAPGCIVQN ATNLY
//
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