ID J7S664_KAZNA Unreviewed; 434 AA.
AC J7S664;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Nucleoside transporter FUN26 {ECO:0008006|Google:ProtNLM};
GN Name=KNAG0D04850 {ECO:0000313|EMBL:CCK70224.1};
GN OrderedLocusNames=KNAG_0D04850 {ECO:0000313|EMBL:CCK70224.1};
OS Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / KCTC
OS 17520 / NBRC 10181 / NCYC 3082 / Yp74L-3) (Yeast) (Saccharomyces
OS naganishii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1071383 {ECO:0000313|EMBL:CCK70224.1, ECO:0000313|Proteomes:UP000006310};
RN [1] {ECO:0000313|EMBL:CCK70224.1, ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2] {ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Kazachstania naganishii.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC {ECO:0000256|ARBA:ARBA00007965}.
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DR EMBL; HE978317; CCK70224.1; -; Genomic_DNA.
DR AlphaFoldDB; J7S664; -.
DR STRING; 1071383.J7S664; -.
DR eggNOG; KOG1479; Eukaryota.
DR HOGENOM; CLU_021611_3_0_1; -.
DR OMA; GSPWTTK; -.
DR OrthoDB; 517168at2759; -.
DR Proteomes; UP000006310; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002259; Eqnu_transpt.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR PANTHER; PTHR10332:SF90; NUCLEOSIDE TRANSPORTER FUN26; 1.
DR Pfam; PF01733; Nucleoside_tran; 2.
DR PIRSF; PIRSF016379; ENT; 1.
DR PRINTS; PR01130; DERENTRNSPRT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006310};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 58..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 434 AA; 48222 MW; BD1ED7EEF9EA55FB CRC64;
MEVERLIPPL EEMSMFRKLT NTTYLTFLLT GIGLLWPWNN ILSATLYFQD TIFKHTTVYA
QVFTSSMMSV STLASLIFNV YIGTRQHSYV ERVTRGLIWQ IIVFVLLTVL CLVTGSDESR
GAPLWVTFTL VMMLVAMSAM ATALTQNGIL AIANVFGPEF SQAVMLGQAI AGVLPSVVLF
ILLLFSSDGA KGQSQTGILL YFLTTSGVCL VCIALYKSSR ISDKLLILTS QDERESHSLD
NNGGHVPLSL LFKKLKYLVL SIFSTFVVSL SFPVFASAVA VGKLPIKNFQ FIPLVFTIWN
LGDLYGRVIA DLPFFRDASF TPYKTFVYSI ARVATIPLFL YYTRQSIDER HTWWLDIGYL
FLQFVFGVTN GHIVSISFMK VPGQLDSDDE REAAGGFTNI FASVGLTVGS VLSYTLVYLV
AAMRHHVPAP AVDR
//
