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Database: UniProt
Entry: J7S8E5_KAZNA
LinkDB: J7S8E5_KAZNA
Original site: J7S8E5_KAZNA 
ID   J7S8E5_KAZNA            Unreviewed;       160 AA.
AC   J7S8E5;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   12-AUG-2020, entry version 25.
DE   RecName: Full=Mating factor alpha {ECO:0000256|PIRNR:PIRNR001866};
GN   Name=KNAG0F02140 {ECO:0000313|EMBL:CCK70881.1};
GN   OrderedLocusNames=KNAG_0F02140 {ECO:0000313|EMBL:CCK70881.1};
OS   Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC
OS   22969 / KCTC 17520 / NBRC 10181 / NCYC 3082) (Yeast) (Saccharomyces
OS   naganishii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX   NCBI_TaxID=1071383 {ECO:0000313|EMBL:CCK70881.1, ECO:0000313|Proteomes:UP000006310};
RN   [1] {ECO:0000313|EMBL:CCK70881.1, ECO:0000313|Proteomes:UP000006310}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC   / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RX   PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA   Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA   Wolfe K.H.;
RT   "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT   accidents.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN   [2] {ECO:0000313|Proteomes:UP000006310}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC   / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RA   Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA   Wolfe K.H.;
RT   "Genome sequence of Kazachstania naganishii.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; HE978319; CCK70881.1; -; Genomic_DNA.
DR   STRING; 588726.J7S8E5; -.
DR   EnsemblFungi; CCK70881; CCK70881; KNAG_0F02140.
DR   eggNOG; ENOG502S0T3; Eukaryota.
DR   HOGENOM; CLU_136956_0_0_1; -.
DR   OMA; AWHWLEL; -.
DR   OrthoDB; 1438589at2759; -.
DR   Proteomes; UP000006310; Chromosome 6.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-UniRule.
DR   GO; GO:0000772; F:mating pheromone activity; IEA:InterPro.
DR   GO; GO:0007618; P:mating; IEA:UniProtKB-UniRule.
DR   GO; GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IEA:UniProtKB-UniRule.
DR   InterPro; IPR016326; Mating_factor_a.
DR   InterPro; IPR006742; Mating_factor_alpha_C.
DR   InterPro; IPR008675; Mating_factor_alpha_N.
DR   Pfam; PF04648; MF_alpha; 3.
DR   Pfam; PF05436; MF_alpha_N; 1.
DR   PIRSF; PIRSF001866; Mating_factor_alpha; 1.
PE   4: Predicted;
KW   Pheromone {ECO:0000256|PIRNR:PIRNR001866};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006310};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..160
FT                   /note="Mating factor alpha"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003796532"
FT   DOMAIN          1..86
FT                   /note="MF_alpha_N"
FT                   /evidence="ECO:0000259|Pfam:PF05436"
SQ   SEQUENCE   160 AA;  17569 MW;  5100370058664BE4 CRC64;
     MKFSTILSAA ALAASAFAAP IEQPEQDLNS TTIPAEAIIS YLDLEGDKDI AVVPFSNATD
     SGLLFVNTTI LAQANKEAGT PLQKREADAD ANAWHWLRLS YGQPIYKRDA NADADADADA
     WHWLRLSYGQ PIYKRDANAD ADADADAWHW LRLSYGQPIY
//
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