ID J7SL63_MORMO Unreviewed; 327 AA.
AC J7SL63;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=Zinc transport protein ZntB {ECO:0000256|HAMAP-Rule:MF_01565};
GN Name=zntB {ECO:0000256|HAMAP-Rule:MF_01565};
GN ORFNames=MU9_2363 {ECO:0000313|EMBL:AGG31408.1};
OS Morganella morganii subsp. morganii KT.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Morganella.
OX NCBI_TaxID=1124991 {ECO:0000313|EMBL:AGG31408.1, ECO:0000313|Proteomes:UP000011834};
RN [1] {ECO:0000313|EMBL:AGG31408.1, ECO:0000313|Proteomes:UP000011834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KT {ECO:0000313|EMBL:AGG31408.1,
RC ECO:0000313|Proteomes:UP000011834};
RX PubMed=23282187;
RA Chen Y.T., Peng H.L., Shia W.C., Hsu F.R., Ken C.F., Tsao Y.M., Chen C.H.,
RA Liu C.E., Hsieh M.F., Chen H.C., Tang C.Y., Ku T.H.;
RT "Whole-genome sequencing and identification of Morganella morganii KT
RT pathogenicity-related genes.";
RL BMC Genomics 13:S4-S4(2012).
CC -!- FUNCTION: Zinc transporter. Acts as a Zn(2+):proton symporter, which
CC likely mediates zinc ion uptake. {ECO:0000256|HAMAP-Rule:MF_01565}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+)(out) + Zn(2+)(out) = H(+)(in) + Zn(2+)(in);
CC Xref=Rhea:RHEA:71195, ChEBI:CHEBI:15378, ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01565};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_01565}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_01565}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass
CC membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|HAMAP-
CC Rule:MF_01565}.
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DR EMBL; CP004345; AGG31408.1; -; Genomic_DNA.
DR RefSeq; WP_004235512.1; NC_020418.1.
DR AlphaFoldDB; J7SL63; -.
DR GeneID; 69678655; -.
DR KEGG; mmk:MU9_2363; -.
DR eggNOG; COG0598; Bacteria.
DR HOGENOM; CLU_007127_2_0_6; -.
DR Proteomes; UP000011834; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005385; F:zinc ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR CDD; cd12833; ZntB-like_1; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR HAMAP; MF_01565; ZntB; 1.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR InterPro; IPR023714; Zn_transp_ZntB.
DR PANTHER; PTHR46494; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR46494:SF3; ZINC TRANSPORT PROTEIN ZNTB; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519, ECO:0000256|HAMAP-
KW Rule:MF_01565};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_01565}; Ion transport {ECO:0000256|HAMAP-Rule:MF_01565};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01565};
KW Reference proteome {ECO:0000313|Proteomes:UP000011834};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01565};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01565}; Transport {ECO:0000256|HAMAP-Rule:MF_01565};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|HAMAP-Rule:MF_01565}.
FT TRANSMEM 268..289
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01565"
FT TRANSMEM 301..321
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01565"
SQ SEQUENCE 327 AA; 36706 MW; 2B37950C3CCE9701 CRC64;
MSALYGSAFQ GTDPICRVQF DGEGGCTPVD VNAVAGIKEP VWLHLDYLSA DNQRWLRETE
LLPPQARDGL TNNVIRPRTL RIGEGALITL QTINNNDGDR PDQLVAFRIW ICGSYIISTR
HRKVHSIQTI QDDLQNGEGA KNTGEWLAEA AFCITDEVAD FIEDLHDTLI DMEDAILDQH
IPARGELALL RKQLIVLRRY MAPQRDVFSR LASERYTWLS EQDRHQLTDV SDRLGRIIDD
IDSCIARTSV ISDEITNMMA DAMNRRTYTM SLLAMVFLPT TFLTGLFGVN LGGIPGGDFP
FAFSLFCVGL AGVIGFVAWW LRKSNWL
//
