ID J8PKI5_SACAR Unreviewed; 891 AA.
AC J8PKI5;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Rsc2p {ECO:0000313|EMBL:EJS42590.1};
GN ORFNames=SU7_2351 {ECO:0000313|EMBL:EJS42590.1};
OS Saccharomyces arboricola (strain H-6 / AS 2.3317 / CBS 10644) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=1160507 {ECO:0000313|EMBL:EJS42590.1, ECO:0000313|Proteomes:UP000006968};
RN [1] {ECO:0000313|EMBL:EJS42590.1, ECO:0000313|Proteomes:UP000006968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H-6 / AS 2.3317 / CBS 10644
RC {ECO:0000313|Proteomes:UP000006968};
RX PubMed=23368932; DOI=10.1186/1471-2164-14-69;
RA Liti G., Nguyen Ba A.N., Blythe M., Mueller C.A., Bergstroem A.,
RA Cubillos F.A., Dafhnis-Calas F., Khoshraftar S., Malla S., Mehta N.,
RA Siow C.C., Warringer J., Moses A.M., Louis E.J., Nieduszynski C.A.;
RT "High quality de novo sequencing and assembly of the Saccharomyces
RT arboricolus genome.";
RL BMC Genomics 14:69-69(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJS42590.1}.
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DR EMBL; ALIE01000145; EJS42590.1; -; Genomic_DNA.
DR AlphaFoldDB; J8PKI5; -.
DR HOGENOM; CLU_007728_2_0_1; -.
DR OrthoDB; 1334586at2759; -.
DR Proteomes; UP000006968; Chromosome XII.
DR GO; GO:0016586; C:RSC-type complex; IEA:InterPro.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd04717; BAH_polybromo; 1.
DR CDD; cd05521; Bromo_Rsc1_2_I; 1.
DR CDD; cd05522; Bromo_Rsc1_2_II; 1.
DR Gene3D; 2.30.30.490; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR037382; Rsc/polybromo.
DR InterPro; IPR048047; RSC1/2_bromodom.
DR InterPro; IPR035700; Rsc1/Rsc2_Bromo.
DR PANTHER; PTHR16062:SF19; PROTEIN POLYBROMO-1; 1.
DR PANTHER; PTHR16062; SWI/SNF-RELATED; 1.
DR Pfam; PF01426; BAH; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00439; BAH; 1.
DR SMART; SM00297; BROMO; 2.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR PROSITE; PS51038; BAH; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 2.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Reference proteome {ECO:0000313|Proteomes:UP000006968}.
FT DOMAIN 35..103
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 296..366
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 409..527
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT REGION 149..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 232..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 602..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 664..691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 843..866
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..196
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..681
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 843..859
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 891 AA; 102682 MW; 4095EC9C57BE541D CRC64;
MMPDDNSNLS TPSSSALYKD LRKEYESLFT LKEDAGLEIS PIFNVLPPKK DYPDYYAVIR
NPVSFNTLKK RIPHYTDAQQ FMNDVVQIPW NAKTYNTRDS GIYKYALVLE KYLKGIIYPN
LKEKYPKLEY PELGPLPDEP GYEEFQQRLR EKAEETARAS AIRAESNSLM NSNEAARKLR
KTRSASVKRE SEPGTDTNND EDYEATDVDI DNSKDADFPD LIRKPLININ SYNRKPLRDN
RSTTSSHSGT PQPLGPRHRQ VSRTQVKRGR PPIIDLPYIQ RMKNVMKVLK KEVLDSGIGL
TDLFERLPDR HRDANYYVMI ANPISLQDIN KKVKTRRYKT FQEFQNDFNL MLTNFRISHR
GDPESIKISN ILEKTFTSLA RFELSKPDRS FIPEGELRYP LDEVTVNNIS YHVGDWALLR
NQNDPQKPIV GQIFRLWKTP DGKQWLNACW YYRPEQTVHR VDRLFYKNEV MKTGQYRDHL
VSNLVGKCYV IHFTRYQRGN PDMKLEGPLF VCEFRYNESD KIFNKIRTWK ACLPEEIRDL
DEVTIPVNGR KFFKYPSPIR HLLPANATPH DRVPEPTMGS PDAPPLVGAV YMRPKMQRDD
LGEYATSDDC PRYIIRPNDS PEEGQVNIET GTITTNAPTT NALPKTGYSS SKLANLRYSR
SSMSLDNQNP VGQQQIPLSR VGSPGAGNPL TVQGLKQHQL QRLQQQQQQH YQQQKRSQVS
RYNIPTIIDD LTSQASRGNL GNIMVDAASS FVLPISITKN VDVLQRTDPH SQTKRSGREE
MFPWKKTKGE ILWFRGPSVI INERTINSGD SHLEQSLNRW SGTSKKRKLE YEEVEETIEN
VTEKEKNEDT MEPDVENERE NLPGPFVLGL RPSAKFTAHR LSLLRPPFSS S
//
