ID J8Q4W8_SACAR Unreviewed; 461 AA.
AC J8Q4W8;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Fth1p {ECO:0000313|EMBL:EJS44738.1};
GN ORFNames=SU7_0255 {ECO:0000313|EMBL:EJS44738.1};
OS Saccharomyces arboricola (strain H-6 / AS 2.3317 / CBS 10644) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=1160507 {ECO:0000313|EMBL:EJS44738.1, ECO:0000313|Proteomes:UP000006968};
RN [1] {ECO:0000313|EMBL:EJS44738.1, ECO:0000313|Proteomes:UP000006968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H-6 / AS 2.3317 / CBS 10644
RC {ECO:0000313|Proteomes:UP000006968};
RX PubMed=23368932; DOI=10.1186/1471-2164-14-69;
RA Liti G., Nguyen Ba A.N., Blythe M., Mueller C.A., Bergstroem A.,
RA Cubillos F.A., Dafhnis-Calas F., Khoshraftar S., Malla S., Mehta N.,
RA Siow C.C., Warringer J., Moses A.M., Louis E.J., Nieduszynski C.A.;
RT "High quality de novo sequencing and assembly of the Saccharomyces
RT arboricolus genome.";
RL BMC Genomics 14:69-69(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC
CC 9.A.10.1) family. {ECO:0000256|ARBA:ARBA00008333}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJS44738.1}.
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DR EMBL; ALIE01000010; EJS44738.1; -; Genomic_DNA.
DR AlphaFoldDB; J8Q4W8; -.
DR HOGENOM; CLU_046738_1_1_1; -.
DR OrthoDB; 1386471at2759; -.
DR Proteomes; UP000006968; Chromosome II.
DR GO; GO:0033573; C:high-affinity iron permease complex; IEA:InterPro.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR004923; FTR1/Fip1/EfeU.
DR PANTHER; PTHR31632; IRON TRANSPORTER FTH1; 1.
DR PANTHER; PTHR31632:SF7; IRON TRANSPORTER FTH1; 1.
DR Pfam; PF03239; FTR1; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00022496};
KW Iron {ECO:0000256|ARBA:ARBA00022496};
KW Iron transport {ECO:0000256|ARBA:ARBA00022496};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022496}.
FT TRANSMEM 6..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 461 AA; 51189 MW; E77EF74DC753E03B CRC64;
MTFEDYFSFQ IFFIFLRESL EIVVIISILL TIVKQGLSVD EDRSVDESSS AGIASPNSNA
NADSTTAFLH AGRTDATATT DSHNCVAGPL NVEEEEELYE YSNELRDQDR EADEHSADNV
KLYQKLKVQI LAGGAFGLLL CMLIGGAFVS IFYHIGTDLW TLSEHYYEGV LSLVASVIIS
VMGLFFLRMG KLREKFRVKL ASIIYSKDNN LLGNKARNGV KFSEKYSFFI LPFITTLREG
LEAVVFIGGI GIDQPLTSIP LSMILATAIS TVFGVFFFKY SSSLSLKICL VVATCFLYLI
AAGLFSKGVW QLELQDYVNK CNGQDMSEVG NGPGSYDISR SVWHVNCCNG EKDGGWMIFT
AIFGWTNSAT VGSVISYNVY WLVLIIALRL LMAEEKYGYI PYIPISWQKK RIMKRLSIAK
ASLDLKHHTS ELNSSTSDPD SQRRSKDSSV PLIIDSHGST N
//
