ID J8Q7Z0_ALKAL Unreviewed; 318 AA.
AC J8Q7Z0;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Arsenic resistance protein {ECO:0000313|EMBL:KGA96927.1};
DE SubName: Full=Arsenite transporter {ECO:0000313|EMBL:AFV25839.1};
GN ORFNames=AJ85_21310 {ECO:0000313|EMBL:THG88816.1}, BalcAV2569
GN {ECO:0000313|EMBL:AFV25839.1}, BALCAV_0213310
GN {ECO:0000313|EMBL:KGA96927.1};
OS Alkalihalobacillus alcalophilus ATCC 27647 = CGMCC 1.3604.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX NCBI_TaxID=1218173 {ECO:0000313|EMBL:KGA96927.1, ECO:0000313|Proteomes:UP000002754};
RN [1] {ECO:0000313|EMBL:AFV25839.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 27647 {ECO:0000313|EMBL:AFV25839.1};
RA Attie O., Jayaprakash A., Sachidanandam R., Shah H., Paulsen I., Morino M.,
RA Ito M., Krulwich T.;
RT "A Draft Genome for Bacillus alcalophilus strain ATCC 27647.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KGA96927.1, ECO:0000313|Proteomes:UP000002754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AV1934 {ECO:0000313|EMBL:KGA96927.1,
RC ECO:0000313|Proteomes:UP000002754};
RX PubMed=25395643;
RA Attie O., Jayaprakash A., Shah H., Paulsen I.T., Morino M., Takahashi Y.,
RA Narumi I., Sachidanandam R., Satoh K., Ito M., Krulwich T.A.;
RT "Draft Genome Sequence of Bacillus alcalophilus AV1934, a Classic
RT Alkaliphile Isolated from Human Feces in 1934.";
RL Genome Announc. 2:0-0(2014).
RN [3] {ECO:0000313|EMBL:THG88816.1, ECO:0000313|Proteomes:UP000297014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.3604 {ECO:0000313|EMBL:THG88816.1,
RC ECO:0000313|Proteomes:UP000297014};
RA Yang J., Diao L., Yang S.;
RT "Draft genome sequencing of Bacillus alcalophilus CGMCC 1.3604.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59)
CC family. {ECO:0000256|ARBA:ARBA00010110}.
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DR EMBL; JX399416; AFV25839.1; -; Genomic_DNA.
DR EMBL; ALPT02000042; KGA96927.1; -; Genomic_DNA.
DR EMBL; JALP01000304; THG88816.1; -; Genomic_DNA.
DR RefSeq; WP_003323092.1; NZ_JALP01000304.1.
DR AlphaFoldDB; J8Q7Z0; -.
DR STRING; 1218173.BALCAV_0213310; -.
DR eggNOG; COG0798; Bacteria.
DR OrthoDB; 3254016at2; -.
DR Proteomes; UP000002754; Unassembled WGS sequence.
DR Proteomes; UP000297014; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0015103; F:inorganic anion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR004706; Arsenical-R_Acr3.
DR InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR43057:SF1; ARSENICAL-RESISTANCE PROTEIN 3; 1.
DR PANTHER; PTHR43057; ARSENITE EFFLUX TRANSPORTER; 1.
DR Pfam; PF01758; SBF; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002754};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 318 AA; 35235 MW; B0E67C8AFB391F33 CRC64;
MSIIEKFQTF IILLAVGVGL LFGQVPFIEA QAGSFILPFL LFMLYGLFLT TPIDNLKKAF
KNIPFLSTNV LINFIWTPIL AWLLGAVFLS DHPALWLGFI LLLVTPCTDW YLVFTSIAKG
NIALSTSVLP INLILQVILL PVYFFIFAGT METVAFSSII ESVVFVLLLP LFLAAVTRYL
FKNRQNILQE KIIPFFATSQ IIFLSLAIVA MFASQGSYLL ANLEVIYLLL IPLLLFFSIN
FLVAQTVGKV LKFSFEDTTS LNLTIIARNS PIALAIVVIA FPEQPLIALA LVIGPLIELP
VLAAVSQILL MMKKRTVA
//
