ID   J8QAV9_SACAR            Unreviewed;       806 AA.
AC   J8QAV9;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 42.
DE   RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE            EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
GN   ORFNames=SU7_0303 {ECO:0000313|EMBL:EJS44714.1};
OS   Saccharomyces arboricola (strain H-6 / AS 2.3317 / CBS 10644) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=1160507 {ECO:0000313|EMBL:EJS44714.1, ECO:0000313|Proteomes:UP000006968};
RN   [1] {ECO:0000313|EMBL:EJS44714.1, ECO:0000313|Proteomes:UP000006968}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H-6 / AS 2.3317 / CBS 10644
RC   {ECO:0000313|Proteomes:UP000006968};
RX   PubMed=23368932; DOI=10.1186/1471-2164-14-69;
RA   Liti G., Nguyen Ba A.N., Blythe M., Mueller C.A., Bergstroem A.,
RA   Cubillos F.A., Dafhnis-Calas F., Khoshraftar S., Malla S., Mehta N.,
RA   Siow C.C., Warringer J., Moses A.M., Louis E.J., Nieduszynski C.A.;
RT   "High quality de novo sequencing and assembly of the Saccharomyces
RT   arboricolus genome.";
RL   BMC Genomics 14:69-69(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJS44714.1}.
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DR   EMBL; ALIE01000011; EJS44714.1; -; Genomic_DNA.
DR   AlphaFoldDB; J8QAV9; -.
DR   HOGENOM; CLU_365223_0_0_1; -.
DR   OrthoDB; 2045814at2759; -.
DR   Proteomes; UP000006968; Chromosome II.
DR   GO; GO:0005634; C:nucleus; IEA:GOC.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   GO; GO:0033260; P:nuclear DNA replication; IEA:InterPro.
DR   CDD; cd14516; DSP_fungal_PPS1; 1.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR   InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR   InterPro; IPR047949; PPS1_DSP.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR   PANTHER; PTHR47550; DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1; 1.
DR   PANTHER; PTHR47550:SF1; DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1; 1.
DR   Pfam; PF00782; DSPc; 1.
DR   SMART; SM00195; DSPc; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 2.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006968}.
FT   DOMAIN          584..782
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50054"
FT   DOMAIN          704..769
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
SQ   SEQUENCE   806 AA;  91745 MW;  6D6C3DA62C2A7B40 CRC64;
     MVLELPSITP DELYDLVRQH QGARWPECKK MFPWAHDISF NEPPDFPFSL AIVKSQPDAN
     NSALLRSSLE ISDIFLSWKV RTSLHEGGAG RETTSETNKF HYPNNVKELL SLLEFQVRQL
     ELHVDDIDLR NVATFCHEHS ILPFLKVDPR GLSLEFKNDP TNKVGSNYGL QSSGQDVWGR
     RGLFRRFDLQ CAKMVEMADN IVIYCSQNGK TTNGETKITA TGAHSRHCLN CTTLALLLQI
     CLKFVKRGYV DCEEPRYKTK LFVCTYQNFN TDIPETLIGT PQLDRQFFNS CTPLNLCSSP
     SEIVCFNNSD SNMVLCERLE LNKLTSATRL DETGLICGNT TDWHSYQIIK KNNLSLPNHF
     QENTSILSLG PLPYDPCNVI SSISQLYNIP NTKQMWKLII KCTSNSSMPS LMKIQSYLRS
     LLYDASLSQE YMHLAFPASG TIGLGNLNIQ SIEILLNVCY LIYQVSQFEG LLTFMHCNDG
     YTETSLLFAA YTIFHFDIPL QDALLKIHPR PFFLFPSDLQ ILGHLQSILR EFSPTREGNR
     KLYADAVKDK DVDFRLNVSS ELFSSIFFMK IPLESNFVNL KGPLPSQILQ HLYLGSLDHA
     QNSALLKSLG ITHIVSVGEV VWWTLDHENT GCPVRPHRSI TMTSTNEVTS SITGTKSRPR
     AGTTINIEQK NDSTMVIKEN RGFQICQIEN LDDNGKDPLF HQLDKILDFI STSEKTGGKV
     LVHCMVGVSR SATVCIAECM RYLQYDLASA YLFVRVRRLN VIIQPNLFFV YELFKWWRKN
     GSYDKNKIID WHIICRGIAE VNKKYT
//