ID J8ZWR5_EDHAE Unreviewed; 305 AA.
AC J8ZWR5;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Transcription elongation factor S-II {ECO:0000313|EMBL:EJW04098.1};
GN ORFNames=EDEG_01620 {ECO:0000313|EMBL:EJW04098.1};
OS Edhazardia aedis (strain USNM 41457) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Edhazardia.
OX NCBI_TaxID=1003232 {ECO:0000313|EMBL:EJW04098.1, ECO:0000313|Proteomes:UP000003163};
RN [1] {ECO:0000313|EMBL:EJW04098.1, ECO:0000313|Proteomes:UP000003163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USNM 41457 {ECO:0000313|EMBL:EJW04098.1,
RC ECO:0000313|Proteomes:UP000003163};
RA Liu Z.J., Shi F.L., Lu J.Q., Li M., Wang Z.L.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000003163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USNM 41457 {ECO:0000313|Proteomes:UP000003163};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Cuomo C.A., Sanscrainte N.D., Goldberg J.M., Heiman D., Young S., Zeng Q.,
RA Becnel J.J., Birren B.W.;
RT "Contrasting host-pathogen interactions and genome evolution in two
RT generalist and specialist microsporidian pathogens of mosquitoes.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJW04098.1}.
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DR EMBL; AFBI03000024; EJW04098.1; -; Genomic_DNA.
DR AlphaFoldDB; J8ZWR5; -.
DR STRING; 1003232.J8ZWR5; -.
DR VEuPathDB; MicrosporidiaDB:EDEG_01620; -.
DR HOGENOM; CLU_037637_4_0_1; -.
DR InParanoid; J8ZWR5; -.
DR OrthoDB; 1383197at2759; -.
DR Proteomes; UP000003163; Unassembled WGS sequence.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd13749; Zn-ribbon_TFIIS; 1.
DR Gene3D; 2.20.25.10; -; 1.
DR Gene3D; 1.10.472.30; Transcription elongation factor S-II, central domain; 1.
DR InterPro; IPR003618; TFIIS_cen_dom.
DR InterPro; IPR036575; TFIIS_cen_dom_sf.
DR InterPro; IPR001222; Znf_TFIIS.
DR PANTHER; PTHR11477:SF0; IP08861P-RELATED; 1.
DR PANTHER; PTHR11477; TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01096; TFIIS_C; 1.
DR Pfam; PF07500; TFIIS_M; 1.
DR SMART; SM00510; TFS2M; 1.
DR SMART; SM00440; ZnF_C2C2; 1.
DR SUPFAM; SSF46942; Elongation factor TFIIS domain 2; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS51321; TFIIS_CENTRAL; 1.
DR PROSITE; PS00466; ZF_TFIIS_1; 1.
DR PROSITE; PS51133; ZF_TFIIS_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:EJW04098.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protein biosynthesis {ECO:0000313|EMBL:EJW04098.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003163};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00472}.
FT DOMAIN 150..262
FT /note="TFIIS central"
FT /evidence="ECO:0000259|PROSITE:PS51321"
FT DOMAIN 264..304
FT /note="TFIIS-type"
FT /evidence="ECO:0000259|PROSITE:PS51133"
FT REGION 73..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..98
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..113
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 305 AA; 35173 MW; 0B0412D3A785B292 CRC64;
MHELTEEIIK YIKRNNLSEI KSLISKNERL PASEINFLLG LSNFDEINDL LQNWPQKEDT
DCIIKSQIDD NLSNKSKERG KDKKESSNPA KNEKNKSSSK KNSFTGTGDS ENDDSSIAIK
KAAFRHTNKM CAKVHDPAAI IQKYKINQAY PDKVLTIFYD VFKNHIKECD FEQAAIVAKK
IVDELVRTDK IKDRELVASK KLNLSNKANP ELCQNVYNGT ISPERYIAMT IEEMKSEDLK
KREEKMKQDQ LMDSQLPKLQ ADTTMFKCSR CKQSKTTYYQ LQTRSADEPM TNYITCCVCG
HKWKF
//
