ID   J9AKP7_WUCBA            Unreviewed;       401 AA.
AC   J9AKP7;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Ribonuclease II/R domain-containing protein {ECO:0000259|SMART:SM00955};
GN   ORFNames=WUBG_14271 {ECO:0000313|EMBL:EJW74820.1};
OS   Wuchereria bancrofti.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX   NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW74820.1, ECO:0000313|Proteomes:UP000004810};
RN   [1] {ECO:0000313|Proteomes:UP000004810}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA   Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M.,
RA   Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA   Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Wuchereria bancrofti.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJW74820.1}.
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DR   EMBL; ADBV01011539; EJW74820.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9AKP7; -.
DR   Proteomes; UP000004810; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR   InterPro; IPR041505; Dis3_CSD2.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR001900; RNase_II/R.
DR   PANTHER; PTHR23355:SF9; DIS3-LIKE EXONUCLEASE 2; 1.
DR   PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR   Pfam; PF17849; OB_Dis3; 1.
DR   Pfam; PF00773; RNB; 2.
DR   SMART; SM00955; RNB; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 2.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022722};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722}.
FT   DOMAIN          69..373
FT                   /note="Ribonuclease II/R"
FT                   /evidence="ECO:0000259|SMART:SM00955"
SQ   SEQUENCE   401 AA;  45632 MW;  FB84227A7C5A1199 CRC64;
     MVEWQATAQF ARGKLYKSLG LAGDIEAETE GLLLANDVDT REFSQAALSS LPITEAVEWK
     IDEKEFKYRK DFRDETVFTI DPSTARDLDD ALHIKPISNC DGAGNPGWEV GVHIADVSHF
     VQFGTELDHW AFNRGTSVYL VHKVIPMLPQ MLCEELCSLN PDVDRLTFSV VWKINDQGEI
     FDEWFGRTII RSCCKLSYEH AQDFIVNPEK DFVSSELPKI FNGKKSDEVK EAILRLNKIA
     VILRKKRFEN GSINFEMPKL NFTLDETSGM PNGLCLSERK EANFLVEEFM LLANMAVARK
     IELSFPKTAL LRRHPPPKIK KEFKYRKDFR DETVFTIDPS TARDLDDALH IKPISNCDGA
     GNPGWEVGVH IADVSHFVQF GTELDHWAFN RGTSVYLVHK S
//