ID J9DXT3_9PROT Unreviewed; 706 AA.
AC J9DXT3;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=LPS-assembly protein LptD {ECO:0000256|HAMAP-Rule:MF_01411};
DE Flags: Precursor;
GN Name=lptD {ECO:0000256|HAMAP-Rule:MF_01411};
GN ORFNames=IMCC14465_02510 {ECO:0000313|EMBL:EJW21857.1};
OS alpha proteobacterium IMCC14465.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; PS1 clade.
OX NCBI_TaxID=1220535 {ECO:0000313|EMBL:EJW21857.1, ECO:0000313|Proteomes:UP000004836};
RN [1] {ECO:0000313|EMBL:EJW21857.1, ECO:0000313|Proteomes:UP000004836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC14465 {ECO:0000313|EMBL:EJW21857.1,
RC ECO:0000313|Proteomes:UP000004836};
RX PubMed=23209213; DOI=10.1128/JB.01888-12;
RA Yang S.J., Kang I., Cho J.C.;
RT "Genome Sequence of Strain IMCC14465, Isolated from the East Sea, Belonging
RT to the PS1 Clade of Alphaproteobacteria.";
RL J. Bacteriol. 194:6952-6953(2012).
CC -!- FUNCTION: Involved in the assembly of lipopolysaccharide (LPS) at the
CC surface of the outer membrane. {ECO:0000256|HAMAP-Rule:MF_01411}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. {ECO:0000256|HAMAP-Rule:MF_01411}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- SIMILARITY: Belongs to the LptD family. {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_01411}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJW21857.1}.
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DR EMBL; ALYF01000002; EJW21857.1; -; Genomic_DNA.
DR AlphaFoldDB; J9DXT3; -.
DR STRING; 1220535.IMCC14465_02510; -.
DR eggNOG; COG1452; Bacteria.
DR Proteomes; UP000004836; Unassembled WGS sequence.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR Gene3D; 2.60.450.10; Lipopolysaccharide (LPS) transport protein A like domain; 1.
DR HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR InterPro; IPR020889; LipoPS_assembly_LptD.
DR InterPro; IPR007543; LptD_C.
DR InterPro; IPR005653; OstA-like_N.
DR PANTHER; PTHR30189; LPS-ASSEMBLY PROTEIN; 1.
DR PANTHER; PTHR30189:SF1; LPS-ASSEMBLY PROTEIN LPTD; 1.
DR Pfam; PF04453; LptD; 1.
DR Pfam; PF03968; LptD_N; 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|HAMAP-Rule:MF_01411};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01411};
KW Reference proteome {ECO:0000313|Proteomes:UP000004836};
KW Signal {ECO:0000256|HAMAP-Rule:MF_01411}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT CHAIN 23..706
FT /note="LPS-assembly protein LptD"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT /id="PRO_5009015747"
FT DOMAIN 32..122
FT /note="Organic solvent tolerance-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03968"
FT DOMAIN 282..641
FT /note="LptD C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04453"
SQ SEQUENCE 706 AA; 79327 MW; 417F014E5EECA39C CRC64;
MRSIFLAGFI MCLCMTPLQV KAQNQNDNQA LIEADSMSFE QDTEIVSASG NVTIQYRGRE
LRADTITWDQ KSDRIIASDN VILIDTDGTR VTTQSAELRD EMKQATLKKF SLMMKNNLSF
KGETASRQAG KSTKISKAIF TACKPCKNNP NAAPTWQLRS GETIYDETGE TIFHKNVRLE
MRGVPVFYFP YLVHPAPDVK KRSGFLFPDI KSSTDTGADI ALPYFINLAP DYDLTLTPRL
IANGGSMLGF DWRQKIPQGT YSIAGNGLWV DEDKNVDNDK TFRGNIEGKG VFKLNENWRA
GFNYWWLSDK SFMRRYDIND ADYFTSQAYL RKTSGRNIID VRLLDFKTSI VDIDEDAQPE
VAPQIRTAHY FENLAGGDLR LSSDFLSLSR KNGTDVTRAV AETEWTRQSI LKSGQILDYF
GGIRGAYHDY EIDNNGQNLS DNSAVVLGHA GAKWRMPFIK RQAAGAVIIE PTAQVIIANE
ETSQSSIPNE DSPSTEFDSL NIFDVYRHTG FDRFDTGNRL DVGVNTLFEA DNGSSYSMFV
GKSYRDKATT QPTIGTKSGK KASDWLLDFD LQQASGFGFN GQLRFDDDNQ RLIRSDGEIS
ASIKQAHFAL RYTHLDASIT SDGSDREEAR GSLDINLSEN WRLNSYVRYD VEREQRLKNS
IGLTYRDDCT DISLTFNQSF TQNGNIGPRN GIAFKIILRT LGGSNR
//
