GenomeNet

Database: UniProt
Entry: J9FE14_WUCBA
LinkDB: J9FE14_WUCBA
Original site: J9FE14_WUCBA 
ID   J9FE14_WUCBA            Unreviewed;      1313 AA.
AC   J9FE14;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   31-JUL-2019, entry version 36.
DE   SubName: Full=RNase3 domain-containing protein {ECO:0000313|EMBL:EJW85584.1};
GN   ORFNames=WBA_LOCUS10783 {ECO:0000313|EMBL:VDM19744.1}, WUBG_03506
GN   {ECO:0000313|EMBL:EJW85584.1};
OS   Wuchereria bancrofti.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX   NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW85584.1, ECO:0000313|Proteomes:UP000004810};
RN   [1] {ECO:0000313|Proteomes:UP000004810}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E.,
RA   Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA   Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA   Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Wuchereria bancrofti.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EJW85584.1}
RP   NUCLEOTIDE SEQUENCE.
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A., Borenstein D., Chapman S.B., Chen Z.,
RA   Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA   Heilman E.R., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Richards J., Roberts A.,
RA   Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA   White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Wuchereria bancrofti.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:VDM19744.1, ECO:0000313|Proteomes:UP000270924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; ADBV01001083; EJW85584.1; -; Genomic_DNA.
DR   EMBL; UYWW01012217; VDM19744.1; -; Genomic_DNA.
DR   InParanoid; J9FE14; -.
DR   Proteomes; UP000004810; Unassembled WGS sequence.
DR   Proteomes; UP000270924; Unassembled WGS sequence.
DR   GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   GO; GO:0016075; P:rRNA catabolic process; IEA:InterPro.
DR   CDD; cd00048; DSRM; 1.
DR   CDD; cd00593; RIBOc; 2.
DR   Gene3D; 1.10.1520.10; -; 1.
DR   HAMAP; MF_00104; RNase_III; 1.
DR   InterPro; IPR014720; dsRBD_dom.
DR   InterPro; IPR011907; RNase_III.
DR   InterPro; IPR000999; RNase_III_dom.
DR   InterPro; IPR036389; RNase_III_sf.
DR   Pfam; PF00035; dsrm; 1.
DR   Pfam; PF14622; Ribonucleas_3_3; 1.
DR   Pfam; PF00636; Ribonuclease_3; 1.
DR   SMART; SM00358; DSRM; 1.
DR   SMART; SM00535; RIBOc; 2.
DR   SUPFAM; SSF69065; SSF69065; 2.
DR   PROSITE; PS50137; DS_RBD; 1.
DR   PROSITE; PS00517; RNASE_3_1; 1.
DR   PROSITE; PS50142; RNASE_3_2; 2.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000004810,
KW   ECO:0000313|Proteomes:UP000270924};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT   DOMAIN      771    949       RNase III. {ECO:0000259|PROSITE:PS50142}.
FT   DOMAIN     1001   1129       RNase III. {ECO:0000259|PROSITE:PS50142}.
FT   DOMAIN     1156   1231       DRBM. {ECO:0000259|PROSITE:PS50137}.
FT   REGION      186    219       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   1313 AA;  149547 MW;  291888A9CCBC626B CRC64;
     MFSNPGLNLP RINLPQQAVL PVLAPEVSRF GCSSSSGTVN MLPTAGGQAA RNVPPLIISH
     NTSANLSAMR PLLPVSNSSE QISDVHCRPS RNVVGCPKPL FSDIERYQWS SASAVERSQF
     VRTPGSRNSR SLPSLRDVSR VTVKQNLHAR EVGVSDDTVC TLTSDCGIST TEPVDISDED
     FNYVSNEEEH AEHKSNNWNT MKTRYRKRRR EQSSSGESES EQGNLCVLVS FLAKGKDIPR
     WQKLTKEDFV DTILSDTDDE IDQVEQTVAM SGFYSRSIPE EKFYCINDVG DCCATEELKK
     LHKRFRLEII EKIAKEKESQ PKSDPPNILA FHDNCKCGHH SDTETESESC DSDDCVDDSD
     ERSGNVSVDE QQTDSKDKIT RVKMSESKKH STVAKREVIR KRNHPAILHS DVCFNEIGQM
     NDGPECRCSW AAKKSGLRHN KYAGETVIEK CDLSSSNSHR LWHYILYTEP NPNTVVRRPT
     KINHRGRTYE LEGFSVFFHK SLPSNFPQTP LSKWTSEYNI KFMEENIPTN FTIEDLELFH
     HYLFTDIMEM YDLKKYPLDN TDGCPYYHCM PRFVCNLPDG GKEILPMSIV MTYLIESYHC
     LVTESEAQVL KQDADAFRDF AENVRGSLVM NANKRPSTIR VDLIDRPDFL PNNSDTLFPL
     ITHFGVRPSS HTYNSNAEYQ KMSKEYLRMR KILAMKPRVS AEERGKLAQK ASQLKALRND
     SQLKRDFVMS VSSRNFYSTG LFPDIVQHGL LLILACAHVR FQWSLQVYEQ ERIHYVFKNR
     SLLELALTHP SYRTNYGTNS DHARNTLNNC GVRSSKQRVH DRLVQQQLSA KKRGFHTLME
     IMSKLGSKKA EQSPLNHNER LEFLGDAVIE FITTIHLFYM FSELDEGGLA TYRSTMVQNK
     NLALLAKKIG LDEFMLYAHG PDLCHESDLR HAMANAFEAM MAAIYLDAGI DECDRIFGHA
     MFADSKELLS TWFDLEDHPL KRDNPNGDRH LINGVPALQL LTELEKNIGI TFKHIRVLAK
     AFTRRNIGFN NLTLGHNQRL EFLGDTVLQL ITTDYLYKHF PYHHEGHLSI LRTCLVSNRT
     QSVICDDIGM TKYLVTPKVM QKSGLPVLRV KDKADLVEAF LGALYVDRGF DYCKIFCRIC
     FFPRLKFFII AQHWNDPKSQ LQQCCLTLRQ MDGGEPDIPE YRTIAVEGPT NTRIYKVAVY
     FRKKRLAVGC GHTMQLAQMR AAENALIKRS DLFPTLKNTA KHSTMQNRRE NGLGAKMKCE
     LADRTKQRML FDSTHVSQSD FATGSSLTDG TQTSRPHIIS LLDLKFDADG CLI
//
DBGET integrated database retrieval system