ID   J9FE32_WUCBA            Unreviewed;      1010 AA.
AC   J9FE32;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=Myosin motor domain-containing protein {ECO:0000259|PROSITE:PS51456};
GN   ORFNames=WUBG_03480 {ECO:0000313|EMBL:EJW85609.1};
OS   Wuchereria bancrofti.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX   NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW85609.1, ECO:0000313|Proteomes:UP000004810};
RN   [1] {ECO:0000313|Proteomes:UP000004810}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA   Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M.,
RA   Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA   Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Wuchereria bancrofti.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJW85609.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ADBV01001071; EJW85609.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9FE32; -.
DR   Proteomes; UP000004810; Unassembled WGS sequence.
DR   GO; GO:0071944; C:cell periphery; IEA:UniProt.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd21759; CBD_MYO6-like; 1.
DR   Gene3D; 1.20.58.530; -; 1.
DR   Gene3D; 3.30.70.1590; -; 1.
DR   Gene3D; 6.10.220.10; -; 1.
DR   Gene3D; 3.40.850.10; Kinesin motor domain; 2.
DR   Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR   Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR049016; MYO6_lever.
DR   InterPro; IPR001609; Myosin_head_motor_dom.
DR   InterPro; IPR008989; Myosin_S1_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR13140; MYOSIN; 1.
DR   PANTHER; PTHR13140:SF745; UNCONVENTIONAL MYOSIN-VI; 1.
DR   Pfam; PF21521; MYO6_lever; 1.
DR   Pfam; PF00063; Myosin_head; 1.
DR   PRINTS; PR00193; MYOSINHEAVY.
DR   SMART; SM00242; MYSc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50096; IQ; 1.
DR   PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW   ProRule:PRU00782};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00782}; Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW   ProRule:PRU00782};
KW   Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW   ProRule:PRU00782};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00782}.
FT   DOMAIN          61..702
FT                   /note="Myosin motor"
FT                   /evidence="ECO:0000259|PROSITE:PS51456"
FT   REGION          582..604
FT                   /note="Actin-binding"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT   BINDING         155..162
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ   SEQUENCE   1010 AA;  116620 MW;  5EC18B1B429F09AA CRC64;
     MDVEGLNMHV WAPDDKDGFV LCKIVDIGCE WVTLQRLHQT ETETFQAFYD NIFPAGEDIS
     RDVDDNCSLI YLNDGSLLNN CRLRYNRKQF YTYVANILIA INPYEQISSL YDIEMVHKYK
     GKSLGTLPPH IFAVADKAYR DMMSNHESQS VIISGESGAG KTESQKHIIR FLCESWGHLV
     GTIEQRILEI STILESFGNA KTACNNNSSR FGKFVEIHFN EKGIIVGGFV SHYLLERSRL
     CGQNVCERNY HIFYQLIAGA DDQMANKLKL NKLEIFDYLN KGCMQFFLNK ESSSKVIPGR
     KKYDLDDMRD DLIDDYNDFQ RLLDAFSHIN VSEDIRDGVF EIVAAVLHLG NIEFSDETVD
     FKTELLGIEV IDLRKHLVTR LMQPTRSGTK GTLYAIPLRA SEATAARDAL AKAIYSNLFT
     AIVNKIAECM PFDGSAFSIG VLDTAGFELF EQKVYGIFEL LDNESRLPRS STQHFTRAVH
     EAHICHPCLM VPQSSPRHRT MRDDEGFIIC HYAADVCYDT AQFLNKNNDT LHASLQCLMQ
     QSRKSLVYEL FTDNGFSNTD RRDVSQSKLM NASVGNKFRS QLDILLSKLR ETGTHFVRCI
     KPNSEMKSNQ FNGAQVLLQL KCSGMSSALK VMQRGFPSRI SYLSLYNIYQ KHLPSKLMTL
     DAQLLCKCLF RVVGLEEKDY KFGLTKAFFR HGKFAEFDKI QHLSKENIEN LIERISSWLY
     RFRFRRAQFA VICLVKVERL LAYRAKCRIK IQSAARTYIL HKLYRPRINA LSTLSELLES
     INGMYSLINK LNETDLCKWT TFIVALKEDI KRLKYEMKAK LFELKLNLIF LHYKRILLSF
     LHITSSADRE IFHQCDALVN DAKEKQQVAT NGLLEMQVDR ENFEKEQQSQ LKNEFKMHVL
     ISQQINEKAQ ETQQMTESLD ESLERKVIMI AKEKSQMLEN SHMIQVRDLS KWYYVDIRNG
     INSSDPKLSS ACKNEYYRRM RAYNEWKERN LASKELTYMT EKNGSKGLKQ
//