ID   J9FEL5_9SPIT            Unreviewed;      1305 AA.
AC   J9FEL5;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=WD-40 repeat protein {ECO:0000313|EMBL:EJY76596.1};
GN   ORFNames=OXYTRI_01886 {ECO:0000313|EMBL:EJY76596.1};
OS   Oxytricha trifallax.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX   NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY76596.1};
RN   [1] {ECO:0000313|EMBL:EJY76596.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JRB310 {ECO:0000313|EMBL:EJY76596.1};
RX   PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA   Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA   Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S., Fulton R.S.,
RA   Ly A., McGrath S., Haub K., Wiggins J.L., Storton D., Matese J.C.,
RA   Parsons L., Chang W.J., Bowen M.S., Stover N.A., Jones T.A., Eddy S.R.,
RA   Herrick G.A., Doak T.G., Wilson R.K., Mardis E.R., Landweber L.F.;
RT   "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome
RT   with 16,000 Tiny Chromosomes.";
RL   PLoS Biol. 11:E1001473-E1001473(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJY76596.1}.
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DR   EMBL; AMCR01011289; EJY76596.1; -; Genomic_DNA.
DR   EnsemblProtists; EJY76596; EJY76596; OXYTRI_01886.
DR   OrthoDB; 193409at2759; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   Pfam; PF00520; Ion_trans; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        1002..1020
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1035..1053
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1065..1084
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1112..1133
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1180..1202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          986..1212
FT                   /note="Ion transport"
FT                   /evidence="ECO:0000259|Pfam:PF00520"
SQ   SEQUENCE   1305 AA;  151115 MW;  F6D2701975F0C820 CRC64;
     MSQEKLLPNG SPDLEFLNKN SDNITLSLNT AGLNKSMIRG SVHQDQLLSL LERKDHTEFK
     MRLDLDNSTK PLIPQRITAS TRFILVLLEP EDGQQVIQLY RRYTNQRLFQ SSINATVKDA
     MIYDPLDLDT SIEYSNGNGH LIFVLNDCNI GSGVRQAFMV LQFSGTQVLS QDIFQATSSW
     FKLRYGSVSD NMQHIGIMFN YEINGDDGKN YPGYDCPCKC FVKFFNYKNG KIYTVSEVPL
     EVFSNRQGIH PKLTFLRNNT QALIATLSQK LILVNVVDGQ QLSTVSITGN SNINLGYYFD
     VQQYFLIDRT SQTEWKIDVV DNEIQLKKQE LFTGIDQEEI SQYASNSNAY QYAAKSKCAM
     QSTATHSTHL SLLDNLPFEF TMSGVRYSRN ICLPNTQVLV AIQEQEPFEV YSVDMSGLDI
     NYLYTQKTSN KKFEYAVDQS QGYSRLMLRN YKQDKTGNES KTQNIINLQS YLDQLFQGEN
     IKESEVQNLQ ILKDLIVFKR NNHFEVYDSE KRQLIGKYFG TAIKFSDSGN AFNLHVGAFN
     YSVYTKQTDD QLSYVKTIPL LKHVAKRVDF LPGSDTQLVI FEDMLKQLLI RDIEKNEIRL
     IFKKVNFEYS EYKLVSDQLI LIDETIKIDN EKVHQKVLYN IVENYPEHRF AQNESILDIS
     LSNDKMYWYI CTPNEIRVVN AQNFNNIICV YKIKNVLKIA EKHDQTYLLC EKESHNLVYS
     VSTLNPKQRL LQFNSSAYVQ KQLLMYLKNE EVENKEQYIR AYQFLFEQGM INTYFSTTGM
     TFLHYLVKNH TPDLIRAYFE NSPDRLHYMN DFNDCSPLEY AATNKKVQHL NIILEYFINY
     PERIVMNRSD FLTLMECNLN NAKVLFSKIF VTPEFYKCGL PYSITSTDDI LVRPTHGEML
     GIHMTQSLEE ELNSYEQGED EKVFKYIVSK FDYNFERGSR SSIEFLQKYA DQDSEEVIRS
     DIRLIVQNKF QECQGFLRAQ AASFMILLVL VFVKQIFFPE SVLIIAIMLV LNAFFVGYEF
     NQISRAGLGQ YFSTIWNYID IYGFVSLFVV NVYEAIEISA GNHSILADSS LVLVFSLTIM
     ALLLRGMSHL RIFDNLRYLI NMVIEIMKDM SSFMILLIYW IFGINIVFFQ LFLNKKISSA
     EIGEGHEEGQ NLEYFLENLK MTYRLAFGDF SPDEYTSLEW LVFILSSVFI PLVLFNLIIA
     IMGDTYDRVQ TSAKCVDLKE QANLVLEVEE LMYWKRDVGE GDKKKILICF NEELSEDTNN
     DSAQWEGKIK GLQKSMVRIE SKIIDLSKTN EAILSTLASL KKKAN
//