ID J9FG45_WUCBA Unreviewed; 773 AA.
AC J9FG45;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Serrate RNA effector molecule homolog {ECO:0000256|ARBA:ARBA00017364};
DE AltName: Full=Arsenite-resistance protein 2 homolog {ECO:0000256|ARBA:ARBA00030701};
GN ORFNames=WBA_LOCUS215 {ECO:0000313|EMBL:VDM06829.1}, WUBG_00498
GN {ECO:0000313|EMBL:EJW88587.1};
OS Wuchereria bancrofti.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW88587.1, ECO:0000313|Proteomes:UP000004810};
RN [1] {ECO:0000313|EMBL:EJW88587.1}
RP NUCLEOTIDE SEQUENCE.
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Genome Sequencing Center for Infectious Disease;
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R.,
RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B., Mehta T.,
RA Park D., Pearson M., Richards J., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Haas B.,
RA Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Wuchereria bancrofti.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000004810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M.,
RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Wuchereria bancrofti.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:VDM06829.1, ECO:0000313|Proteomes:UP000270924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ARS2 family.
CC {ECO:0000256|ARBA:ARBA00005407}.
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DR EMBL; ADBV01000084; EJW88587.1; -; Genomic_DNA.
DR EMBL; UYWW01000023; VDM06829.1; -; Genomic_DNA.
DR AlphaFoldDB; J9FG45; -.
DR InParanoid; J9FG45; -.
DR OMA; HLRMCEE; -.
DR Proteomes; UP000004810; Unassembled WGS sequence.
DR Proteomes; UP000270924; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR InterPro; IPR039727; SE/Ars2.
DR InterPro; IPR007042; SERRATE/Ars2_C.
DR InterPro; IPR021933; SERRATE/Ars2_N.
DR PANTHER; PTHR13165; ARSENITE-RESISTANCE PROTEIN 2; 1.
DR PANTHER; PTHR13165:SF0; SERRATE RNA EFFECTOR MOLECULE HOMOLOG; 1.
DR Pfam; PF04959; ARS2; 1.
DR Pfam; PF12066; SERRATE_Ars2_N; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000270924}.
FT DOMAIN 111..220
FT /note="SERRATE/Ars2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12066"
FT DOMAIN 558..727
FT /note="SERRATE/Ars2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04959"
FT REGION 1..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 662..773
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..37
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 679..696
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 751..773
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 773 AA; 88364 MW; FDCF2B09B19A9D36 CRC64;
MGDSDDEYHR RGGRDKFARE RNDYPDRIRR DYDYDRRGGG SGGGGGSGGG SNTYQRGDYA
NGSSMKRSSS RRDDYVSSTK RSRIDSASDT YDPVMKTSAD EEPVPVMMTF KKFLATQDDS
ITDEEAIAKY SEYKLEFKRQ ELHKFFLAHK DEEWFRLKYH PEDSGRRKAE QKENVLRRLE
IFQNLYDEGC IDKLQIDYDY APEIIRVMDT LVVKLEGGTE DDIAALKSEK IDDESVLELK
KLKNETKRKT AEINGEENKS KQEKGGENPN DDGAITDSDD EKEKQCRNVG NEESAKNEEE
MIRQKKKMLL HKTSSIFLRN VAPNITMEEI ETACKRFPGF LRVGLADPVP DRKFYRRGWV
TFRRDVNIKE ICWNLNSVRI KECDLGAVIN RDIARRVRSV NGITGHKQVA QNDLRQAAKL
AALYDKKNGL YQSENQEERQ SSFELDVVAQ SQNPLLKNLT DFLIEEANAE EEELLGISSE
GIIEEDQKVP FQRDDALIAR LDRIITYLRI VHSIDFYNHG EYPNEDVMPN RCGMMHVRGA
PPSSSQWGTD DNGRTLVAQK FVTDFIAGFN NRIETALMSE TSLNELELDN LGRKDTEKEV
ESFITANCVE LAKDKWLCPL SGKKFKGPEF IRKHLTTKHG EKLDQVRQEV VYFNNYLTDS
KRPQNLEVKP TQASPQVAPP REERRERERD YDGDRSRASG GGGGGNFSYG DRDRRGYERN
TGGSSGGRYA SSYGGRNYDR GGTSRYWESS GGGRRDPREP VTYKDLDAPE DIF
//
