ID   J9FKZ1_9SPIT            Unreviewed;       303 AA.
AC   J9FKZ1;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Carbonic anhydrase {ECO:0000313|EMBL:EJY78816.1};
GN   ORFNames=OXYTRI_24018 {ECO:0000313|EMBL:EJY78816.1};
OS   Oxytricha trifallax.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX   NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY78816.1};
RN   [1] {ECO:0000313|EMBL:EJY78816.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JRB310 {ECO:0000313|EMBL:EJY78816.1};
RX   PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA   Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA   Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S., Fulton R.S.,
RA   Ly A., McGrath S., Haub K., Wiggins J.L., Storton D., Matese J.C.,
RA   Parsons L., Chang W.J., Bowen M.S., Stover N.A., Jones T.A., Eddy S.R.,
RA   Herrick G.A., Doak T.G., Wilson R.K., Mardis E.R., Landweber L.F.;
RT   "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome
RT   with 16,000 Tiny Chromosomes.";
RL   PLoS Biol. 11:E1001473-E1001473(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJY78816.1}.
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DR   EMBL; AMCR01009256; EJY78816.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9FKZ1; -.
DR   EnsemblProtists; EJY78816; EJY78816; OXYTRI_24018.
DR   OrthoDB; 751784at2759; -.
DR   GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd03124; alpha_CA_prokaryotic_like; 1.
DR   Gene3D; 3.10.200.10; Alpha carbonic anhydrase; 1.
DR   InterPro; IPR041891; Alpha_CA_prokaryot-like.
DR   InterPro; IPR001148; CA_dom.
DR   InterPro; IPR036398; CA_dom_sf.
DR   InterPro; IPR023561; Carbonic_anhydrase_a-class.
DR   PANTHER; PTHR18952; CARBONIC ANHYDRASE; 1.
DR   PANTHER; PTHR18952:SF266; CARBONIC ANHYDRASE 2, ISOFORM A; 1.
DR   Pfam; PF00194; Carb_anhydrase; 1.
DR   SMART; SM01057; Carb_anhydrase; 1.
DR   SUPFAM; SSF51069; Carbonic anhydrase; 1.
DR   PROSITE; PS51144; ALPHA_CA_2; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..303
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003822980"
FT   DOMAIN          23..264
FT                   /note="Alpha-carbonic anhydrase"
FT                   /evidence="ECO:0000259|PROSITE:PS51144"
SQ   SEQUENCE   303 AA;  32935 MW;  EAC3394404B86BFC CRC64;
     MKSNITAILI ILGLVSSANA GGGSIDYSSG GSNWKDGVCS NGTSQSPIDL PTSFSSSSDN
     SKKLVKSDVL DMIMNEGLIA GVKLNDLGTT YQIDFTNGIL AMWTPAGVMG TYNLLQFHVH
     APSEHTFDGK HYDLEIHFVH NQPGSSQLAV VSVSFDVEDG GNKSNDFIDA LHVDYKNQSA
     LTIPTMKLLG KLNYHNLYHY QGSLTTPPCS EVVNWLVVND PQPISATQLK NFNDKWMSNS
     TFAHGHGNNR LVQPINSRYV YLKANADSLL ASSGISSLMQ GLQKTLAGVL SLYFFYSIQT
     IFN
//