ID   J9FNA1_WUCBA            Unreviewed;      2022 AA.
AC   J9FNA1;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=HEAT repeat-containing protein 5B {ECO:0008006|Google:ProtNLM};
GN   ORFNames=WUBG_00208 {ECO:0000313|EMBL:EJW88879.1};
OS   Wuchereria bancrofti.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX   NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW88879.1, ECO:0000313|Proteomes:UP000004810};
RN   [1] {ECO:0000313|Proteomes:UP000004810}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA   Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M.,
RA   Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA   Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Wuchereria bancrofti.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HEATR5 family.
CC       {ECO:0000256|ARBA:ARBA00008304}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJW88879.1}.
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DR   EMBL; ADBV01000029; EJW88879.1; -; Genomic_DNA.
DR   Proteomes; UP000004810; Unassembled WGS sequence.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000357; HEAT.
DR   InterPro; IPR040108; Laa1/Sip1/HEATR5.
DR   InterPro; IPR046837; Laa1/Sip1/HEATR5-like_HEAT.
DR   PANTHER; PTHR21663; HYPOTHETICAL HEAT DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR21663:SF0; SORTING OF APICAL PROTEINS; 1.
DR   Pfam; PF02985; HEAT; 1.
DR   Pfam; PF20210; Laa1_Sip1_HTR5; 1.
DR   SUPFAM; SSF48371; ARM repeat; 2.
PE   3: Inferred from homology;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REGION          1206..1225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2022 AA;  222790 MW;  394E9EE7C5DC9BB0 CRC64;
     MEQSNSLLLN EEALSFCTDS KKPVFVYEWL RYLDRILPAT QKADIKSVQK KLIEQLTTRI
     LAAPGPLIRE LLAKCIAQVY SVGDTYNLFE TINICNDILK GRDDSPTHLP VKLAALHCLG
     AMYETLGRLV GRSYEESYHH MAKWLKNAES QGRAELLYTF AKMVKGLGIA ASSIHKDLYK
     VLKTQISDRV MMVRTAAVNC LTVLIPEYPF LYMNEVENVC TLCFKALESS NYEVRHAVAQ
     LFAALLCTAM NPPRRYMSIP GSKNQHSASS LKVLTIEDCF GMLSHGFLRG GIGGFLKTGA
     VAVTGGQKEI RIGVALAYVA LLRELGPLWL EKNLVFVIKH LMDVIAKCGP LAYTNNPIQA
     VEVIYMRRCI GYILRSTIGT VLGEQAQIAV CRQLGAVLAD CISSFTDYNL DSGTERMLGP
     EAYANAQTTI IVLSEISCLV RQIGTAVTPL FTEASGIMEP VFACLLHPVQ AARIAASWCL
     RCITVSVPSQ LTPLIDRCIS RLEHMKSCGD AISGYSFALS ALLVSSVECK LGIPHAKSRQ
     VFTIAEDMIR TASQASSLAQ VKSQAGWILV SAVLKLGGTT VHDCIGRLLP LWKSSFPRSA
     KEAEAEKNRG DAFTWFCTLE ARNGALTSMT MFVEYSPNLM TDHTIRTIIQ AVECSLTTIS
     HISALIRTFG TKLRALMTFM RIRIYQLLSH ISPKYYEHTY ALLLRELVAD LTLSDNGQSV
     ATTSLLSSLC PGVDKSLLGA WLNDTDQVFI ELEMHPSQNF ICGAIDNDPL CIVRVTIDDA
     LWWPEPLCHT VTVVNEAINV YGRIYPFVPP KHQLQMAEHF AKCVKGTKNI IRQQSIQKNV
     FGCLLASFKT VSEQKGLHLE GQALQKAYID LIIPCLSHAV PLIRCAAAEA LGRLAQVVGD
     AQFVASMAQY SFDKLKSCRD ANNRTGYALT LGSLHRYVGS LGSGQHLNTS VSILLALAQD
     ATSSLVQSWS LVALGLIADT GGGMFRGYVE PSLSLCLKLL LDTPPSNVDV IRCTGKFVSA
     LISTMGPELQ LVGAVEGTRT SFLIGLVMML NSSDSLVQAE AISCLQQLHL FTPRHVHLDR
     LVVQLCKLLS SPHLILRKVS VCCLRQLVQR EAKEVREHSQ TLVPQGIMNN MGRNVESGLP
     ETGLEGALLA MLDVETDIKL KQDIKETLIS LVQAVSTDFL SYWLSLCKDI LASSMGADVR
     SAIQAEEKGS SSVKDEEDEH ENMDDDVTLQ SASIVSREEK MKVIPRWPSR VFATELVQRV
     MSVCETERAH FDLALAKELQ ISSGGRADYL VLHLSDLVRM SFMGATSDNT SLRLAGLACL
     QDVINRFSSI PEPEFPGHVI LEQFQAQVGA ALRPAFTADT PSDVTAAACQ VCSTWIGSGV
     AQDLNDLRRV HQLLVSSLGK LTHGSINTQL YSESAATLEK LAILKAWAEV YIVAVDQKKQ
     KKVVNATAVK NEEKCSFLQE SLLSLVSPEL NSLINCWLAA LRDSALLSLP PEFKNQLPLE
     GGAYYTAECA DVCKEYYRVS WPPILLAACI WLKQNDFELQ QNFDDSELCL RSLRNLLACN
     WSQKVLMRNA QLPIEVINVL YRLILTRENL RTQQLCADVV MTVLDAAQYS ITLDNDKGQQ
     KSTVKDGYKG AEGTSDGLRP VGSLAFAVLE VSLCLLIPQI NSALMKSKSA APLHYRRYSR
     LPIESNNLIK IGLNILTRIP MLCSPDGVVV VLPSILYLIL GVLHESSLID KEQLVPDAPF
     GHVSIAAATA MQVLKTLLST IPNDSTYPKW MSVMKSTLIS LLNMTEDSKV DGAVIMLAVA
     VFVTSSPPQL VMGNTGLLRR ICKLFQTYLE SEHKQVVVKC MQSLASIFGR REICYPFIAE
     LVPNILNRIR PFVTSDSEGI PETPQSEDVV IVQEAVRILE IALSVADQKK QLAIVNLIVQ
     LLGTFLCDNP VTYYRVLPIS VRKLHDYALD RLNVVGPSHP DEFKQVLLSF PALKSKIEES
     IRHHSNRSMQ QTQRATGAGK CEHIPLPAIK LKLDFRAFNP AN
//