GenomeNet

Database: UniProt
Entry: J9HN51_9BACL
LinkDB: J9HN51_9BACL
Original site: J9HN51_9BACL 
ID   J9HN51_9BACL            Unreviewed;       303 AA.
AC   J9HN51;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   08-MAY-2019, entry version 29.
DE   RecName: Full=Prephenate dehydratase {ECO:0000256|RuleBase:RU361254};
DE            Short=PDT {ECO:0000256|RuleBase:RU361254};
DE            EC=4.2.1.51 {ECO:0000256|RuleBase:RU361254};
GN   Name=pheA {ECO:0000256|RuleBase:RU361254};
GN   ORFNames=URH17368_1673 {ECO:0000313|EMBL:EJY55608.1};
OS   Alicyclobacillus hesperidum URH17-3-68.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Alicyclobacillaceae;
OC   Alicyclobacillus.
OX   NCBI_TaxID=1200346 {ECO:0000313|EMBL:EJY55608.1, ECO:0000313|Proteomes:UP000035011};
RN   [1] {ECO:0000313|EMBL:EJY55608.1, ECO:0000313|Proteomes:UP000035011}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=URH17-3-68 {ECO:0000313|EMBL:EJY55608.1,
RC   ECO:0000313|Proteomes:UP000035011};
RX   PubMed=23105079; DOI=10.1128/JB.01612-12;
RA   Wang P., Li L., Chen X., Jiang N., Liu G., Chen L., Xu J., Song H.,
RA   Chen Z., Ma Y.;
RT   "Draft Genome Sequence of Alicyclobacillus hesperidum Strain URH17-3-
RT   68.";
RL   J. Bacteriol. 194:6348-6348(2012).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O;
CC         Xref=Rhea:RHEA:21648, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:18005, ChEBI:CHEBI:29934;
CC         EC=4.2.1.51; Evidence={ECO:0000256|RuleBase:RU361254};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis;
CC       phenylpyruvate from prephenate: step 1/1.
CC       {ECO:0000256|RuleBase:RU361254}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EJY55608.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AKZN01000039; EJY55608.1; -; Genomic_DNA.
DR   RefSeq; WP_006447016.1; NZ_AKZN01000039.1.
DR   EnsemblBacteria; EJY55608; EJY55608; URH17368_1673.
DR   PATRIC; fig|1200346.3.peg.1726; -.
DR   OrthoDB; 1280729at2; -.
DR   UniPathway; UPA00121; UER00345.
DR   Proteomes; UP000035011; Unassembled WGS sequence.
DR   GO; GO:0004106; F:chorismate mutase activity; IEA:InterPro.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR008242; Chor_mutase/pphenate_deHydtase.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF00800; PDT; 1.
DR   PIRSF; PIRSF001500; Chor_mut_pdt_Ppr; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Aromatic amino acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Complete proteome {ECO:0000313|Proteomes:UP000035011};
KW   Lyase {ECO:0000256|RuleBase:RU361254};
KW   Phenylalanine biosynthesis {ECO:0000256|RuleBase:RU361254}.
FT   DOMAIN        2    196       Prephenate dehydratase.
FT                                {ECO:0000259|PROSITE:PS51171}.
FT   DOMAIN      216    300       ACT. {ECO:0000259|PROSITE:PS51671}.
FT   SITE        189    189       Essential for prephenate dehydratase
FT                                activity. {ECO:0000256|PIRSR:PIRSR001500-
FT                                2}.
SQ   SEQUENCE   303 AA;  32211 MW;  D714098F28FFBE8B CRC64;
     MRLYYLGPEG THSHEASALA AQQLILASAE LCPLPTFSDV LAACFASPPG EAFACVPIEN
     SIQGSVWQVW DEVMRACSIA PSQASPAWGI LAAVTQPIHQ FAIYQEGTDP LQVTTVLSHP
     QALAQCAQTL KVRYPNAVPS TVSSTAEAVR QVAMQSAKSA VAIGSRRAAA VYGLAYDEAP
     LEDHQGNVTR FAVIGPREVS LPKPTALEWT DETASLCLRG VPHRPGGLVG ALQAFAAANL
     NLTRLESRPV GDQLGHYVYY LDVSVAGLCD EGQLSLQHVV EELATHGTEV ISLGVYPVYR
     NPG
//
DBGET integrated database retrieval system