ID   J9HWY1_9SPIT            Unreviewed;       629 AA.
AC   J9HWY1;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=EF hand family protein {ECO:0000313|EMBL:EJY64903.1};
GN   ORFNames=OXYTRI_14949 {ECO:0000313|EMBL:EJY64903.1};
OS   Oxytricha trifallax.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX   NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY64903.1};
RN   [1] {ECO:0000313|EMBL:EJY64903.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JRB310 {ECO:0000313|EMBL:EJY64903.1};
RX   PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA   Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA   Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S., Fulton R.S.,
RA   Ly A., McGrath S., Haub K., Wiggins J.L., Storton D., Matese J.C.,
RA   Parsons L., Chang W.J., Bowen M.S., Stover N.A., Jones T.A., Eddy S.R.,
RA   Herrick G.A., Doak T.G., Wilson R.K., Mardis E.R., Landweber L.F.;
RT   "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome
RT   with 16,000 Tiny Chromosomes.";
RL   PLoS Biol. 11:E1001473-E1001473(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJY64903.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AMCR01021826; EJY64903.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9HWY1; -.
DR   EnsemblProtists; EJY64903; EJY64903; OXYTRI_14949.
DR   OrthoDB; 3936962at2759; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   Gene3D; 1.10.238.10; EF-hand; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   PANTHER; PTHR46311; CALCIUM-BINDING PROTEIN 8-RELATED; 1.
DR   PANTHER; PTHR46311:SF5; EF-HAND DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   SMART; SM00054; EFh; 2.
DR   SUPFAM; SSF47473; EF-hand; 1.
DR   PROSITE; PS00018; EF_HAND_1; 2.
DR   PROSITE; PS50222; EF_HAND_2; 2.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          261..296
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          297..332
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   REGION          185..206
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          517..540
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   629 AA;  72638 MW;  F704D0168A7F6938 CRC64;
     MKKSHLTGKP IFGLSYEISH KPIRVVESKC SSRNEGFDSQ LFMDKRINER YFDSNTNQSI
     DQDAVRIKSN LSQAYRSNKL RTERLTKPTT SSLNHRVKSL NHNLLNLNIT LQKPQTQQTT
     KREIHGHGFA YLNNQRAQQE NLETINLNEN SLENPKILTN TCSHLNLRVL NDQVNKARGS
     YNLSGGSFDS SQRLQSGNSQ QSFESRRNIN KYLKDKTDFQ NQRSKSNNYA LPNSLLFQAE
     STKRQWLDKH GKSNFVVFTS EELQKLRKYF KELDTDGSGS IGLEELEQPL ISLGLCKTRE
     EVQHIMDSVD EDKSGQIEFD EFLTIIKGAQ GKLSLKEQKQ EKDRSHTATL DNQQFKKTLD
     RENISAQSQR DIRIVTRITR KNTLPPLAKN KTTRVNQLNK ENSQILEQPS VVNSIRSRDP
     YQKVKKSIEV QNVDEGQDQK IFNFFKNLTS GNLKSQENPN IPFQLFLSGY RRKRILDAVM
     KNSENINNSN TKSVLKIYHD FIQNVEQDEN ISVSNHFDQH SQSSDNYKSG GPSSHNQRNN
     VNIQSSLNQF DSNAFVTKTS DLEFHQEQKA THNRYNLKQQ QNNNDFDDFN SIGYNYDQSI
     VEADTLLKDA RVLQEFNPDI FSQILNQQH
//