ID J9ISV0_9SPIT Unreviewed; 2021 AA.
AC J9ISV0;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=RZ-type domain-containing protein {ECO:0000259|PROSITE:PS51981};
GN ORFNames=OXYTRI_24190 {ECO:0000313|EMBL:EJY78648.1};
OS Oxytricha trifallax.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY78648.1};
RN [1] {ECO:0000313|EMBL:EJY78648.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JRB310 {ECO:0000313|EMBL:EJY78648.1};
RX PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S., Fulton R.S.,
RA Ly A., McGrath S., Haub K., Wiggins J.L., Storton D., Matese J.C.,
RA Parsons L., Chang W.J., Bowen M.S., Stover N.A., Jones T.A., Eddy S.R.,
RA Herrick G.A., Doak T.G., Wilson R.K., Mardis E.R., Landweber L.F.;
RT "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome
RT with 16,000 Tiny Chromosomes.";
RL PLoS Biol. 11:E1001473-E1001473(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJY78648.1}.
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DR EMBL; AMCR01009408; EJY78648.1; -; Genomic_DNA.
DR EnsemblProtists; EJY78648; EJY78648; OXYTRI_24190.
DR OrthoDB; 276853at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR046439; ZF_RZ_dom.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF341; NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF20173; ZnF_RZ-type; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51981; ZF_RZ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 1923..2000
FT /note="RZ-type"
FT /evidence="ECO:0000259|PROSITE:PS51981"
FT REGION 1..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 400..449
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 10..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..85
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..151
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..217
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2021 AA; 234461 MW; 85DA840D5F0E6518 CRC64;
MERRYQVKRG GQTANLNQTN ANLNQSQQQQ QQNPQAVARN QEEEKKSYNS QPQDSNSVQE
VRYIPRSAAQ NHISQTNNQE EFKSSRGNRG GLGVNGRGRG RVADNGDYEA RGGRSNRGDR
GNRGNRGGRS DRVGSTDRES RGNRDGRGNI GDRGGRGNIG DRGGRGNRED RGGRGNREDR
GGRGNREDRG GRGNRGDRGG RNDTDGRSGR GNRVDRGNFR GRGIQPQNND RQLIQDREQI
QPHVQNERPF RQRTQQDNRR PRYFTVDQIQ QLLDKPLAEI VEQLTEYPQL SQSIDATNYS
SNTYQDQRTT IYSAFNDSDF YQNLQRNYFT DLNISIRSRD EYLQKLEELD ILIEVFSLLV
DKFRTSANIY PVLQLKSFLK DELPDIQVKH DFIGYSKPKV QELQVKAKAL KQKVRDARTL
VQQQEEVKIE EVKRRQNQIN NRDEDYKQQA PNDFRLIRVV PTIEELSQRD RPFLRAIPSG
EARFRNPQDY LDLIFRLLRE DAICPLRKGY QLMKRQHQLD QNTFRLEMRN TGCRLYDNVV
IQDVSTSRNS QEMVLTLRIF ERRNQNWLTS KRLLNGSLLM ISKDNFNTLD FCIVADKDPK
EMANTSLRFK FVDIQVQLIK SDANNHYEED ENPIQVNQAI DFYVNNKNLS FQMIESSAYF
EAYNHILHKL KEMASWNTLP FEKYLLGLQK NIDSPPLWDS LSQQQRAQLQ NSIRNAILDA
KLDQSQVKAI NSCFYKELAI IQGPPGTGKT YVGEHFVRIL MQNIKLWRKQ KGPILLVCYT
NHALDQFLNL IKKYTQNFIR FGGRCKDEGL SKHQIREFIR SRDDLRYPIG YRDCIQDLDD
IQLKVADQKL LFQFNTLGVM NKLVDFDEKV LDGALNAITK EFHRIANQTA AELYRFQQME
AESQQQLEYQ KSVYENVRTH IYSMLEKDSD ISVVFWLGII DTQKYVEDIW DWYMSGNNVE
EPDINEDDFD QRELDYIQGN MNTNLTFKQR KRIYLSIRDK IRNLTQQYDP YLQSDFFGNS
KTIQECIQIG QRIQGINHYS ANFQPFNLTL NQRWQLNNYF LAQNRSENPQ GNLVSLASQY
ESIYKRKKQL DTLTQVKAIR KADVVAMTTT GCAKFNDILR NVQFSIVIVE EAAEVFEAHI
ISSLSEHSEH LVLIGDHQQL KPAPAVYELE KKYNLSMSLF ERLVKNDYEY TTLSTQRRMR
PEISSIVKLI YPNLVDGEKV LNYPVIRGID KSLYFFDHEN QEDRDEGLMS KFNKFESNMI
ERFTKYLLQQ NYKPERITIL SLYMAQSLHI KRQIMEKYPR DHEMRNVKVI TVDNFQGEEN
DIIILSLVRS NQSNQIGYLK VSNRVCVALS RAKHGMYIFG NATCLYKHVD RQMNQQHAQV
EEQQQLWLEV LNYLKEKQFI GETLNLCCEK HKNVTTIKNP EDFQNVPEGG CKLPCNARLN
CGHSCESICH YYEITPQDSS GHKKTKCLKQ CERENPCGHP CSFKCFECID KLQPCQTMID
KTFDICGHST RVKCHLFDTA KCYDQCQKVK PCGHNCQKYC HVDCSQQKCG VNVLKRLPCG
HEMELKCYQT PEDFVANDRF GCPKKCDVLL DCGHPCKETC GSCTKNIFHK TCEVKLDKAY
QCGHVKSQFC GTLSVLCQQK CENKCIHNHC PKKCYEPCDL CLEPCLIQCE HSKCGKKCSQ
PCNKELCIQR CDLILECSHR CIGLCGDQCP KICKVCQPDH ETFEIFFGYE QEPETTFVQI
DCGHILDAKS LDTYISTQQQ DGHVKLPECP KCKQPIKKCL RYQNSINQTL QDMNQIKLKT
LKQHEQLMVQ FDTLPQKFKQ LQGRLHEIKI EKQFKIQQVF KLWESIYRKS NDNESLLKDC
TIKLELMSFI IAFGNYIHQY DQHQQNDASI YSFCQVSIEK ILSKRFALPE GLKSIMRTKA
ELIDREYNFK ATMQMVIKAL NLGPGHYYKC PNGHYYAIGD CGGAMEVSKC PDCGATIGGS
NHALVQGNQH AGEFDNSSRA AWDTHGFDQQ VLNGQVDLNE I
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