ID J9JCB9_9SPIT Unreviewed; 4002 AA.
AC J9JCB9;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=VSP domain containing protein {ECO:0000313|EMBL:EJY88060.1};
GN ORFNames=OXYTRI_20110 {ECO:0000313|EMBL:EJY88060.1};
OS Oxytricha trifallax.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY88060.1};
RN [1] {ECO:0000313|EMBL:EJY88060.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JRB310 {ECO:0000313|EMBL:EJY88060.1};
RX PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S., Fulton R.S.,
RA Ly A., McGrath S., Haub K., Wiggins J.L., Storton D., Matese J.C.,
RA Parsons L., Chang W.J., Bowen M.S., Stover N.A., Jones T.A., Eddy S.R.,
RA Herrick G.A., Doak T.G., Wilson R.K., Mardis E.R., Landweber L.F.;
RT "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome
RT with 16,000 Tiny Chromosomes.";
RL PLoS Biol. 11:E1001473-E1001473(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJY88060.1}.
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DR EMBL; AMCR01000691; EJY88060.1; -; Genomic_DNA.
DR EnsemblProtists; EJY88060; EJY88060; OXYTRI_20110.
DR OrthoDB; 337149at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00064; FU; 3.
DR Gene3D; 2.60.120.200; -; 3.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006212; Furin_repeat.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR011936; Myxo_disulph_rpt.
DR NCBIfam; TIGR02232; myxo_disulf_rpt; 1.
DR SMART; SM00261; FU; 4.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 3.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 3286..3303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 3323..3346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 3358..3383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 3440..3460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 3472..3490
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 3502..3523
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 3629..3754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3770..3822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3861..3882
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3629..3710
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3722..3754
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3787..3801
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3802..3822
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4002 AA; 458353 MW; 96BCA9ED6EA9AD43 CRC64;
MPINIEHVAQ VKVETTTQLI TVQQIQGGTT HTSTSTPQVK VEAVSIWFRV GISKSINSYT
LYYNLNPAFT KTSQTFSAVR TPYLTSGYVG VNQGSYTNQY MFARDFVFYQ NFAASLADMN
QIFYQFQKIS LEKSYIAAYY KFEYCQTGKL YNIYDTYYNN RLTASYQSYA NFEEDVLLQQ
IKAQRSIDFP GYTYTAVTNK YDKSLLITST IEVRGIQKDV ASFTIELWAK FQSNTNQRFY
FVTECAVIAS CTQMLFGIDT STSLMHLTLS NVFMSQTMNN PTVDFTTWNH FAITFDEHIP
QSYPSHYQYI LNNQFALRTS STSIANFQFT SSILYFAKPQ NSAGTFPNVY MKELRIWAPM
RTQHDVNYFR RQYMDQVYPA SLVQYWKFEY DFQNLFSIKD TSLNNLGQEA TTNLNSQWDT
QALVLCENGT SYVGGSNNCQ ANQAMEEHIR YFPNSGPRAI YISTNQDFMI EVWQYLWSDS
QTWYVGEHTG CGLGQCQYYI QGGNLIYKRF LLDLFPDTLK SGVTARQWHH YFYYVKSSEV
DFYFDTENMG TQGYGKEYRA YTNFGTENIQ NLKYMILKNY KNTVPNPTEY PFLIFYLKLY
APYYSTDIYS DHLLYDLTQR NSPLATVNNV QATLSNIADQ HQQVILCTNG QFWDGLSCRF
DHLVVQSVTS TASRTQKVQL GQIVYLEDYF TLMFWFSQKV DGTSTIQSQG HPSVQLFNLD
LIRNEASSAS SYYQFQFCGS SAYTQYYGTR LGNGWYHLAI SSVSLTLKSY VINAFGTVLV
NQNNHGSHTS CKTIAVPSTS VNLLSQTLRN IALKDFVFMN DFPSISQLTH VAFTPHRYKS
AALIYNRLDP DSHYGWIQDD IYSIKSQINY KTSSASFQQK YYEWTYDPMS PIVCNDTDQY
IPSSMLCGQL YYREKTASQC MITTWDYSPV RDGSGSVPAT TYIGIGIWIK ISVKSTSVPA
VMTYIQLGIS STAYIRLYGY NGSPYLSGST IVNPSYNLNG DVFGDNGSGT AQGITARFTE
NKFDERCVNQ YCYMFLQRGG ATPQLKLFRG GQLAVTQNYA YSRMLISNSM TIGCAGAAGN
LQNWQGNIQH VRLFYGSDMT TSHQMFLHQP RRLHSTGALN YLPLSVGPSS YAGSEIDLRY
DTTNNYAQAK TYNTATDFNF VSNWQYLALT YKSSGDKLFL VNNQVAITAT NLQNWPAGTY
SIYTNSNYIY RLYIWTRARS QLEILRNLYR VINQKTYYKY LVLSYNPVWG YEFGEYSKQL
NEYWTFGKQF QLQEDVEDVG SNSLPYCVKS QISNSYECQD ERLFIFSSSD GYNNLDLRVY
ELIKSSTQIQ VEFWMIMYES LAIGDIFKIS FASGKSVAVK EDSVTALRVY INSVQKASTT
RPSSSSYSWN HFNFQFDLLN NMNLYINGDT LAFGPISILS DSLGSPNSEY ISICSGTCNY
FSIKDLKVWG ELYTYSADEV QSISMVIGTN SNLFAYYPFN EMKGYTLHEQ AFQYTMNLQN
YDHQNYNKVM RWEDIDFYEQ NSNSPQPCQI NHIYDSDTQS CELVQDQYQT IEFYATNDPQ
VLSFQTTQKF SREWSIEFYF KFQVYNDVLT PSDYVPIFEY DSACSSQGTK FSARVQETSL
LRYIKATLVD GSQTTIFTST NSISEQTWYY LTLSNNFWTN QLTNYLDLDE STVQNSNAMQ
KLANCQYKVA YNSAGLNTNK RIRLKELRIW NSALSRQDFG IYDRINMPKR YPEIAAIIKF
KDLDFYEEIY GISNSRATFQ DYVIKYDTQI RNNCPVGFRQ YTANGLADCE NYPGRFLRVL
GLTQLTFDIS SAMQTRYQDN QYDFSIQFTL ASVYNIDAAY IPVGYTYTYD YFFIDNFLRI
RSIDFNNYNM IFTTGTSTTN TLTVAHSRDW RHILINVIPS QQKIEVYINQ VLSLTIPVSS
ISDVPYLQTV RFGSTTLTEQ NMYLVGPTII FPPLTQYQIQ YHGVGARLNA QKYDHSFLYQ
RIGYSSIYDA SPIQLYDTAQ AATFSITATG SSYSNHHYYL YCMGEMDTDS RTGSGCLPKG
VLKMKRARAS ASFSNAINFK WHFSTGLWVN FDTLVSSTVL DFFYLPDIID FQLSPTKNLQ
VTNYKATAAS TTISTSFQVS EKIWYGFAGV KTSQGFWNVY NENTLIQNIT DTTSSYYGKL
TSMQFGDITL AGHIVRIKNI FGVARQMKPG EIYESLHKRL SVLDYRYSML FYYRMDEDQS
NVIYDSSYYK NKFTLPTPTN GYLTWDKSWE QVLFNEETWT DDFKTSQYMD RGILFKNSQT
PKLTLLPTLT TMSQEYTLEF CLYLSAINVN SVILGITQLT QVTVTGSNKI SFFPNLSNQL
SLTFIDFTIT GKWLYMAVGN SIEKSVSYIM SDSNDNDVYI SAVGYSSTLT LPVSFYIGGT
TASSTFSGYL RHVKIYNSFR SIGQARATLH HEMSPYIGLD YTNLVALFPL TEPIGTKLRE
QISGIQTTFD SDVYEINKYP SRPVICSGDT KYSNRGYCEP NQRFLQLQDT LTFSIENTVS
KCFSITQWMY LKTFSVFKIQ VQDRMSLVVD YSNDKITFRN NLDTLDLLTL SSQVQSSYVN
QWTYLTGKFC QEISSIHLAI TYKDSTSTLV TSDKGNQKYS MSFSDSGQKS VSILLSGIAN
PELYLKELQI YSTYISTYWN SNYGFLAKNK HQNALAAYFK MDESAGQYLY NYAQASVNKA
SQFIYGGSSE FKWVFEVSIS GSTTIADTTF YCVDTHTELV DKHCEVWNGC DSSCFFDNEC
YGPLAANCLE PPTDSYYFDS IQENYYLDCY QLCKECNTNW QNDCSSCLTD VIFYEDQCLL
ECPINTYEGI KSGTTVKTCF TCDNPDCVCD VDDLSECYRC IDGSSKLYIL SPEHDCITIC
SNGTYYNVES YTCDICSELC TICDGPSNGQ CQACIETYIL IDGVCLQPSC PFSQFFNYTT
LLCEDCHESC NGCTGSTSQD CVDCQDEFQK SNSQCTACEL ITGLKSPMKN GRCDEICGDG
KNLGVYECDD GNLISGDGCN ENCEKEDGFN CGTSGCLKID KPRPYVKSLS KNNDITIGFD
QAISVAEGDL SSSDLEIVIY KPDGSKVKFS WTASISSDYS RTNSFKISLT PKESLQGNEK
ISIYFKPEGK VFKSKEYSYL DANGQQIMNK LNEVEYSDEG LKALAKQAGK AAAQVLTASL
GVNFIIQLLM QGSMSQMFEL INTIQILYYM PLIQVYYTDF LRESLTSLGS LANIDIPIPG
DDDDDEQSLL NTIFDKKKFK DQPFNEAFEE FGIMGTTFIL TYKSKIVLWA VAVAGFPIFH
IIMKKYKKKN FFRKILIRVD GIYRYNFAIQ AFIELYLEMA ILNFIGLYNL QYDNASQIFA
SIVSLIFFVA VCVIPIFILD IIFENFHRLS SHTFHHRFGT LIENQKLQLN KTLLNMWIPL
FFLRRIIYAA TIVMLQNNGL MQLIISTFIT MWVLAFAIII RPFKTVRANG LTMLNEGTIL
FCFLMSFYFV DKDKSDDDRM KYSYVTILAI IGCVTINLIF LFITMGKQIY EGFIKIKREI
KLLKELWANR KQKNQTQNIS ERQLLGESQK LTNTNRLLIR NIANNQNSLE NSQQIRKAIR
ESESNIRVKN SAARQSEAYE TNNNRLDLST SINVNNTGQT GQTLISQNSP GLRNKQRSQL
FSQNQRQQQE DYFVQYQKPQ DRQNSFTNRN QGQKINQDDQ ANNGRKLQSP TTRDSRFKSS
KKVTFADNAS PNQHPSRNHR FSLDNQDPMN VLTDNDDQQD FKIKLVGQAI SQNKKQKQTS
RNKNRQAKQR LKADKSLSDY NLDSKTPKFN ESQNLTSDNS IPLDTMSDIA VVGSNAQKQQ
LNNQNQSKLL RLIKTQSSNS LYEDNAQKSQ QQPQIDSNSG EFTFKNNIDA KISKKQNKNL
KSQNKGLKLD IMNNNGNNNF GDFIDSNYID NGRNSINVDE HTPLKRKLEE NNEFDQQFML
NDNDILNKFK QGKPKFQDEN VFQFKRNKDK QQPQHHMKNE NN
//
