ID J9JCE6_9SPIT Unreviewed; 625 AA.
AC J9JCE6;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Tr-type G domain-containing protein {ECO:0000259|PROSITE:PS51722};
GN ORFNames=OXYTRI_18888 {ECO:0000313|EMBL:EJY88195.1};
OS Oxytricha trifallax.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY88195.1};
RN [1] {ECO:0000313|EMBL:EJY88195.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JRB310 {ECO:0000313|EMBL:EJY88195.1};
RX PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S., Fulton R.S.,
RA Ly A., McGrath S., Haub K., Wiggins J.L., Storton D., Matese J.C.,
RA Parsons L., Chang W.J., Bowen M.S., Stover N.A., Jones T.A., Eddy S.R.,
RA Herrick G.A., Doak T.G., Wilson R.K., Mardis E.R., Landweber L.F.;
RT "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome
RT with 16,000 Tiny Chromosomes.";
RL PLoS Biol. 11:E1001473-E1001473(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJY88195.1}.
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DR EMBL; AMCR01000545; EJY88195.1; -; Genomic_DNA.
DR AlphaFoldDB; J9JCE6; -.
DR EnsemblProtists; EJY88195; EJY88195; OXYTRI_18888.
DR OrthoDB; 470716at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd04093; HBS1_C_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR PANTHER; PTHR23115:SF188; HBS1-LIKE PROTEIN; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 187..410
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 31..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 112..146
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 34..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 625 AA; 71201 MW; 427474C401C62C00 CRC64;
MSRHKNLKSI VADSYYDEDY YNDYGAEYGN EGGAYGSEDE HKEEQKQIQK AKKKSKKQNL
VDDKVVQEIF DQFNKFFTQE QVKQTLIANY NDKLKTIADL RFKEDKLKQK GKENLKQVIQ
VKKQKVEEEK KQFHAEEEEF KQYEVQLLKK EKSLNAEIEI DHKTLNQIYP EVSYADPQFL
KHLEEDNKTI NLVIIGHVDS GKSTLTGHLL YKLGKVDRQT MHKMEKISDQ YGKSSFKFAY
LLDEGEEERR RGVTIQVGQS YFATENKDFV ILDAPGHQDF VPNMISGASQ ADCAILVVEG
IRQEFQRGFI GGATKEHAIL ARSLGVTQMI VAVNKLDMVE WSQEAYDEIV AQVQPFLMSI
GFRQDNITFI PISGLHGTNL IAKPNEVQEL IRWYDGPTLI ELLDKLKIPK RNISKPLRVC
IYDYYKGTEG NLIGDCISAK IESGIVKEKD HLLLMPLNIM VTVKAIETSD KVIKFAGPGT
LCDMSLHLPP SVDPTYIKSG QVICDPKYPI YQVKEFRCQI VVFDIDIPIT RGQPVTVYSF
SNRISGRISK LESIVNPKSG ETIKKNPRCL LKNQTAIVHV KLEEKTCLEL FSNYRQLGRA
TFRDGQKTLA AGINIELGGP QPLIL
//
