ID J9R630_RIEAN Unreviewed; 327 AA.
AC J9R630;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Pyruvate dehydrogenase E1 component subunit beta {ECO:0000256|ARBA:ARBA00016138};
GN ORFNames=B739_1350 {ECO:0000313|EMBL:AFR35948.1};
OS Riemerella anatipestifer RA-CH-1.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Riemerella.
OX NCBI_TaxID=1228997 {ECO:0000313|EMBL:AFR35948.1, ECO:0000313|Proteomes:UP000006276};
RN [1] {ECO:0000313|EMBL:AFR35948.1, ECO:0000313|Proteomes:UP000006276}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RA-CH-1 {ECO:0000313|EMBL:AFR35948.1,
RC ECO:0000313|Proteomes:UP000006276};
RA Chun C.A., Shu W.M., Kang Z.D., Jia W.X.;
RT "Riemerella anatipestifer vaccine strains.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall
CC conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple
CC copies of three enzymatic components: pyruvate dehydrogenase (E1),
CC dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase
CC (E3). {ECO:0000256|ARBA:ARBA00025211}.
CC -!- SUBUNIT: Heterodimer of an alpha and a beta chain.
CC {ECO:0000256|ARBA:ARBA00011870}.
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DR EMBL; CP003787; AFR35948.1; -; Genomic_DNA.
DR RefSeq; WP_014938277.1; NC_018609.1.
DR AlphaFoldDB; J9R630; -.
DR STRING; 34085.AB406_0433; -.
DR KEGG; rag:B739_1350; -.
DR PATRIC; fig|1228997.3.peg.1346; -.
DR HOGENOM; CLU_012907_1_1_10; -.
DR Proteomes; UP000006276; Chromosome.
DR GO; GO:0004739; F:pyruvate dehydrogenase (acetyl-transferring) activity; IEA:UniProtKB-UniRule.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR43257; PYRUVATE DEHYDROGENASE E1 COMPONENT BETA SUBUNIT; 1.
DR PANTHER; PTHR43257:SF2; PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Pyruvate {ECO:0000313|EMBL:AFR35948.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006276}.
FT DOMAIN 4..179
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 327 AA; 36348 MW; 07B4596D8BD02D4E CRC64;
MKEYTFREVI AQAMSEEMRK DESIYLIGEE VAEYNGAYKA SKGMLDEFGP KRVIDAPIAE
GGFAGISVGA AMNGNRPIVE FMTFNFSLVA IDQIINNAAK MYQMSGGQWN VPIVFRGPTG
SAGQLGATHS QAFESWYANC PGLKVVVPSN PYDAKGLLKT AIQDNDPVIF MESEQMYGDK
MEIPEEEYYI PIGKADIKKE GKDVTLVSFG KIMKLALQAA EELEKEGISV EVIDLRTVRP
LDYDTVLASV KKTNRLVVLE EAWPFGSVAS EITYMVQQKA FDYLDAPIKR ITTPDAPAPY
SAALFAEWFP KLEKVKEEIK KALYIKN
//
