ID J9RKY8_9ACTN Unreviewed; 432 AA.
AC J9RKY8;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Cobalt-precorrin-6B (C5,15)-methyltransferase {ECO:0000313|EMBL:AFR49022.1};
GN ORFNames=KTR9_2385 {ECO:0000313|EMBL:AFR49022.1};
OS Gordonia sp. KTR9.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=337191 {ECO:0000313|EMBL:AFR49022.1, ECO:0000313|Proteomes:UP000003281};
RN [1] {ECO:0000313|EMBL:AFR49022.1, ECO:0000313|Proteomes:UP000003281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KTR9 {ECO:0000313|EMBL:AFR49022.1,
RC ECO:0000313|Proteomes:UP000003281};
RX PubMed=22923396; DOI=10.1128/AEM.02120-12;
RA Chen H.P., Zhu S.H., Casabon I., Hallam S.J., Crocker F.H., Mohn W.W.,
RA Indest K.J., Eltis L.D.;
RT "Genomic and transcriptomic studies of an RDX (hexahydro-1,3,5-
RT trinitro-1,3,5-triazine)-degrading actinobacterium.";
RL Appl. Environ. Microbiol. 78:7798-7800(2012).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005879}.
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DR EMBL; CP002907; AFR49022.1; -; Genomic_DNA.
DR RefSeq; WP_014926745.1; NC_018581.1.
DR AlphaFoldDB; J9RKY8; -.
DR STRING; 337191.KTR9_2385; -.
DR KEGG; gor:KTR9_2385; -.
DR PATRIC; fig|337191.3.peg.2703; -.
DR eggNOG; COG2241; Bacteria.
DR eggNOG; COG2242; Bacteria.
DR HOGENOM; CLU_031955_0_0_11; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000003281; Chromosome.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11644; Precorrin-6Y-MT; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR012818; CbiE.
DR InterPro; IPR006365; Cbl_synth_CobL.
DR InterPro; IPR014008; Cbl_synth_MTase_CbiT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR02467; CbiE; 1.
DR NCBIfam; TIGR02469; CbiT; 1.
DR PANTHER; PTHR43182; COBALT-PRECORRIN-6B C(15)-METHYLTRANSFERASE (DECARBOXYLATING); 1.
DR PANTHER; PTHR43182:SF1; COBALT-PRECORRIN-7 C(5)-METHYLTRANSFERASE; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR PIRSF; PIRSF036428; CobL; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AFR49022.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AFR49022.1}.
FT DOMAIN 17..210
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 432 AA; 45301 MW; BC56324E9A413582 CRC64;
MRSPGAAVTS TVPTSEFVVV GIGADGWPGL GEPARDELRH ARVIYGAARQ LALLDGAAPR
LGAQLRPWRS PMSEHLAELV ETGGVDDAHP DTVHILASGD PMFHGVGASI VARVGADRVR
VYPAVSSASL ACARLGWDLA TTRIVSAVRT EPGVVLGEVT DGARVLVLSR DETTPAAVAE
LLTDAGFGAS AMTVLEQLGG PAEQIATDTA EGWHRRAGDS LNIVAVDCVG PHRTRLPGRA
DEAYEHDGQI TKSTIRALTV CALEPAGAQI LWDIGAGSGS VAIEWLRADD RGLAVAFERD
PERADRLRRN AARHGVAHRL SVRGPAPDEL AAAPQPDAVF IGGGLDEEIL ALAWDALADS
GRLVVNAVTV ENQALVTQRH ADQGGTLRRL SVETVAPLGT MTTWRPALPI VQWSVDKPTT
GLPDAGLAEA VR
//
