ID   J9VFM1_CRYNH            Unreviewed;       179 AA.
AC   J9VFM1;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=Dynactin subunit 6 {ECO:0000256|ARBA:ARBA00016573};
GN   ORFNames=CNAG_03652 {ECO:0000313|EMBL:AFR93157.1};
OS   Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 /
OS   CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=235443 {ECO:0000313|EMBL:AFR93157.1, ECO:0000313|Proteomes:UP000010091};
RN   [1] {ECO:0000313|EMBL:AFR93157.1, ECO:0000313|Proteomes:UP000010091}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H99 / ATCC 208821 / CBS 10515 / FGSC 9487
RC   {ECO:0000313|Proteomes:UP000010091};
RX   PubMed=24743168; DOI=10.1371/journal.pgen.1004261;
RA   Janbon G., Ormerod K.L., Paulet D., Byrnes E.J.III., Yadav V.,
RA   Chatterjee G., Mullapudi N., Hon C.C., Billmyre R.B., Brunel F., Bahn Y.S.,
RA   Chen W., Chen Y., Chow E.W., Coppee J.Y., Floyd-Averette A., Gaillardin C.,
RA   Gerik K.J., Goldberg J., Gonzalez-Hilarion S., Gujja S., Hamlin J.L.,
RA   Hsueh Y.P., Ianiri G., Jones S., Kodira C.D., Kozubowski L., Lam W.,
RA   Marra M., Mesner L.D., Mieczkowski P.A., Moyrand F., Nielsen K., Proux C.,
RA   Rossignol T., Schein J.E., Sun S., Wollschlaeger C., Wood I.A., Zeng Q.,
RA   Neuveglise C., Newlon C.S., Perfect J.R., Lodge J.K., Idnurm A.,
RA   Stajich J.E., Kronstad J.W., Sanyal K., Heitman J., Fraser J.A.,
RA   Cuomo C.A., Dietrich F.S.;
RT   "Analysis of the genome and transcriptome of Cryptococcus neoformans var.
RT   grubii reveals complex RNA expression and microevolution leading to
RT   virulence attenuation.";
RL   PLoS Genet. 10:E1004261-E1004261(2014).
CC   -!- FUNCTION: Part of the dynactin complex that activates the molecular
CC       motor dynein for ultra-processive transport along microtubules.
CC       {ECO:0000256|ARBA:ARBA00034687}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
CC   -!- SIMILARITY: Belongs to the dynactin subunits 5/6 family. Dynactin
CC       subunit 6 subfamily. {ECO:0000256|ARBA:ARBA00007719}.
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DR   EMBL; CP003821; AFR93157.1; -; Genomic_DNA.
DR   RefSeq; XP_012047366.1; XM_012191976.1.
DR   AlphaFoldDB; J9VFM1; -.
DR   GeneID; 23887128; -.
DR   KEGG; cng:CNAG_03652; -.
DR   VEuPathDB; FungiDB:CNAG_03652; -.
DR   HOGENOM; CLU_085418_0_0_1; -.
DR   OrthoDB; 5101at2759; -.
DR   Proteomes; UP000010091; Chromosome 2.
DR   GO; GO:0005869; C:dynactin complex; IEA:InterPro.
DR   CDD; cd04646; LbH_Dynactin_6; 1.
DR   Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR   InterPro; IPR027777; DCTN6.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   PANTHER; PTHR13072; DYNACTIN 6; 1.
DR   PANTHER; PTHR13072:SF0; DYNACTIN SUBUNIT 6; 1.
DR   SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212}.
SQ   SEQUENCE   179 AA;  19309 MW;  A85EBE21F90275B2 CRC64;
     MSRQTLTAHA TSLVCADTDL RGPITIGPNV IIHPRATIYA AAGPIMLGEG CIVEEACIIV
     NRKKDTLRIG ENNHFMVGCR IESPSIGNNN IFQPNSTASA GVIVTDNCII SAGTILLPSP
     THTGEEPETL PPYTVIYGAD SSRRTWDGSG QVAEMALRSK HAEYLREIIP KFNRLRPTA
//