ID J9VLP8_CRYNH Unreviewed; 423 AA.
AC J9VLP8;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=SGNH hydrolase-type esterase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CNAG_00488 {ECO:0000313|EMBL:AFR92620.1};
OS Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 /
OS CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=235443 {ECO:0000313|EMBL:AFR92620.1, ECO:0000313|Proteomes:UP000010091};
RN [1] {ECO:0000313|EMBL:AFR92620.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=H99;
RG The Broad Institute Genomics Platform;
RA Cuomo C., Janbon G.J., Paulet D., Neuveglise C., Dietrich F., Allen A.,
RA Stajich J.S., Heitman J., Kronstad J., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M.D., Poon T., Priest M., Roberts A.D., Saif S., Shea T.D.,
RA Sykes S.N., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus neoformans grubii H99.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFR92620.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=H99 {ECO:0000313|EMBL:AFR92620.1};
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Cuomo C., Gargeya S., Jaffe D., Young S.K., Wortman J., Zeng Q.,
RA Alvarado L., Dietrich F., Allen A., Stajich J.E., Heitman J., Kronstad J.;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AFR92620.1, ECO:0000313|Proteomes:UP000010091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H99 {ECO:0000313|EMBL:AFR92620.1}, and H99 / ATCC 208821 / CBS
RC 10515 / FGSC 9487 {ECO:0000313|Proteomes:UP000010091};
RX PubMed=24743168; DOI=10.1371/journal.pgen.1004261;
RA Janbon G., Ormerod K.L., Paulet D., Byrnes E.J.III., Yadav V.,
RA Chatterjee G., Mullapudi N., Hon C.C., Billmyre R.B., Brunel F., Bahn Y.S.,
RA Chen W., Chen Y., Chow E.W., Coppee J.Y., Floyd-Averette A., Gaillardin C.,
RA Gerik K.J., Goldberg J., Gonzalez-Hilarion S., Gujja S., Hamlin J.L.,
RA Hsueh Y.P., Ianiri G., Jones S., Kodira C.D., Kozubowski L., Lam W.,
RA Marra M., Mesner L.D., Mieczkowski P.A., Moyrand F., Nielsen K., Proux C.,
RA Rossignol T., Schein J.E., Sun S., Wollschlaeger C., Wood I.A., Zeng Q.,
RA Neuveglise C., Newlon C.S., Perfect J.R., Lodge J.K., Idnurm A.,
RA Stajich J.E., Kronstad J.W., Sanyal K., Heitman J., Fraser J.A.,
RA Cuomo C.A., Dietrich F.S.;
RT "Analysis of the genome and transcriptome of Cryptococcus neoformans var.
RT grubii reveals complex RNA expression and microevolution leading to
RT virulence attenuation.";
RL PLoS Genet. 10:E1004261-E1004261(2014).
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DR EMBL; CP003820; AFR92620.1; -; Genomic_DNA.
DR EMBL; CP003820; AGV15311.1; -; Genomic_DNA.
DR RefSeq; XP_012046752.1; XM_012191362.1.
DR RefSeq; XP_012046753.1; XM_012191363.1.
DR AlphaFoldDB; J9VLP8; -.
DR GeneID; 23884290; -.
DR KEGG; cng:CNAG_00488; -.
DR VEuPathDB; FungiDB:CNAG_00488; -.
DR HOGENOM; CLU_063298_0_0_1; -.
DR OrthoDB; 1360401at2759; -.
DR Proteomes; UP000010091; Chromosome 1.
DR GO; GO:0004620; F:phospholipase activity; IEA:InterPro.
DR CDD; cd01824; Phospholipase_B_like; 1.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR035547; Phospholipase_B.
DR InterPro; IPR038885; PLB1.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR PANTHER; PTHR21325:SF31; GH22081P-RELATED; 1.
DR PANTHER; PTHR21325; PHOSPHOLIPASE B, PLB1; 1.
DR Pfam; PF00657; Lipase_GDSL; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
PE 4: Predicted;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..423
FT /note="SGNH hydrolase-type esterase domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015095706"
SQ SEQUENCE 423 AA; 47158 MW; 4BA8F54A8562C646 CRC64;
MWIHRYSPVA QFLLVLVLIP VNCWSLPPHL PKPQLPGKLV PFSRLHECPS LRPRVYPTVA
KDVRPDDFRV IMALGDSITA GLLARGSRSS SASSAPSQVD RQRPLLPSLD IQEYRGLSYP
IGSDPGAITI PEILRHFSPS AEEITGSSKG KHPPVTCLNG WGIKGCAERP EEDGLNAAVS
GSVSAGLLRQ VEDFILPRLK DMEIRKEDWK FVNLGIGAND ICSFCLYPNI TDIDFSGSPK
RFAKDIKHAV NALRKNVPNI IVNIIGLFRV SAIYKLTLKD PYCQPPLFPY PIPHFPLECS
CALLPGPTGD WTRQKMDELG EAYDEAVLEI VREWEKEGDE HFGAIWQPGT AIDLPNYPIT
ALSPIDCFHP SEASHQRMAA GIWNRLTLNL EEKYLPISWD DEIMVRCLEE DDRVSVGMTS
ESF
//
