ID J9VP11_CRYNH Unreviewed; 220 AA.
AC J9VP11;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 22-FEB-2023, entry version 49.
DE RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588};
GN ORFNames=CNAG_05902 {ECO:0000313|EMBL:AFR96222.1};
OS Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 /
OS CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=235443 {ECO:0000313|EMBL:AFR96222.1, ECO:0000313|Proteomes:UP000010091};
RN [1] {ECO:0000313|EMBL:AFR96222.1, ECO:0000313|Proteomes:UP000010091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H99 / ATCC 208821 / CBS 10515 / FGSC 9487
RC {ECO:0000313|Proteomes:UP000010091};
RX PubMed=24743168; DOI=10.1371/journal.pgen.1004261;
RA Janbon G., Ormerod K.L., Paulet D., Byrnes E.J.III., Yadav V.,
RA Chatterjee G., Mullapudi N., Hon C.C., Billmyre R.B., Brunel F., Bahn Y.S.,
RA Chen W., Chen Y., Chow E.W., Coppee J.Y., Floyd-Averette A., Gaillardin C.,
RA Gerik K.J., Goldberg J., Gonzalez-Hilarion S., Gujja S., Hamlin J.L.,
RA Hsueh Y.P., Ianiri G., Jones S., Kodira C.D., Kozubowski L., Lam W.,
RA Marra M., Mesner L.D., Mieczkowski P.A., Moyrand F., Nielsen K., Proux C.,
RA Rossignol T., Schein J.E., Sun S., Wollschlaeger C., Wood I.A., Zeng Q.,
RA Neuveglise C., Newlon C.S., Perfect J.R., Lodge J.K., Idnurm A.,
RA Stajich J.E., Kronstad J.W., Sanyal K., Heitman J., Fraser J.A.,
RA Cuomo C.A., Dietrich F.S.;
RT "Analysis of the genome and transcriptome of Cryptococcus neoformans var.
RT grubii reveals complex RNA expression and microevolution leading to
RT virulence attenuation.";
RL PLoS Genet. 10:E1004261-E1004261(2014).
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC {ECO:0000256|ARBA:ARBA00004180}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004180}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004180}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the adaptor complexes small subunit family.
CC {ECO:0000256|ARBA:ARBA00006972, ECO:0000256|PIRNR:PIRNR015588}.
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DR EMBL; CP003826; AFR96222.1; -; Genomic_DNA.
DR RefSeq; XP_012050620.1; XM_012195230.1.
DR AlphaFoldDB; J9VP11; -.
DR GeneID; 23889186; -.
DR KEGG; cng:CNAG_05902; -.
DR VEuPathDB; FungiDB:CNAG_05902; -.
DR HOGENOM; CLU_061221_2_2_1; -.
DR OrthoDB; 998051at2759; -.
DR Proteomes; UP000010091; Chromosome 7.
DR GO; GO:0030123; C:AP-3 adaptor complex; IEA:InterPro.
DR GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006896; P:Golgi to vacuole transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR CDD; cd14834; AP3_sigma; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR InterPro; IPR016635; AP_complex_ssu.
DR InterPro; IPR022775; AP_mu_sigma_su.
DR InterPro; IPR027155; APS3.
DR InterPro; IPR000804; Clathrin_sm-chain_CS.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR PANTHER; PTHR11753; ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY; 1.
DR PANTHER; PTHR11753:SF2; ADAPTOR PROTEIN COMPLEX AP-3 SMALL CHAIN SIGMA3; 1.
DR Pfam; PF01217; Clat_adaptor_s; 1.
DR PIRSF; PIRSF015588; AP_complex_sigma; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS00989; CLAT_ADAPTOR_S; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|PIRNR:PIRNR015588};
KW Protein transport {ECO:0000256|PIRNR:PIRNR015588};
KW Transport {ECO:0000256|PIRNR:PIRNR015588}.
FT DOMAIN 1..174
FT /note="AP complex mu/sigma subunit"
FT /evidence="ECO:0000259|Pfam:PF01217"
SQ SEQUENCE 220 AA; 24241 MW; 577F7ADE1F294080 CRC64;
MIHAVLIFNT NGKPRLSKFF TPLPPLVQQS LISQIFSLIS DRPAGVCNFL DAPDLVFPTP
KSMVKYRQEE RNDLGLEGGR NGEEVKEMED DTRVIYRHYA TLYFVFVVDG AESELGILDL
IQVFVESLDR AFENVCELDL IFHFDEVYHV LSEIIQGGLV LETNINEISA CVRAATKNRK
ESSASANPLI PSVLAAPGGR GGNRGGSADG ARRWLAAMGV
//
