ID J9W415_CRYNH Unreviewed; 656 AA.
AC J9W415;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 2.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=FCP1 homology domain-containing protein {ECO:0000259|SMART:SM00577};
GN ORFNames=CNAG_05529 {ECO:0000313|EMBL:AFR98955.2};
OS Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 /
OS CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=235443 {ECO:0000313|EMBL:AFR98955.2, ECO:0000313|Proteomes:UP000010091};
RN [1] {ECO:0000313|EMBL:AFR98955.2, ECO:0000313|Proteomes:UP000010091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H99 / ATCC 208821 / CBS 10515 / FGSC 9487
RC {ECO:0000313|Proteomes:UP000010091};
RX PubMed=24743168; DOI=10.1371/journal.pgen.1004261;
RA Janbon G., Ormerod K.L., Paulet D., Byrnes E.J.III., Yadav V.,
RA Chatterjee G., Mullapudi N., Hon C.C., Billmyre R.B., Brunel F., Bahn Y.S.,
RA Chen W., Chen Y., Chow E.W., Coppee J.Y., Floyd-Averette A., Gaillardin C.,
RA Gerik K.J., Goldberg J., Gonzalez-Hilarion S., Gujja S., Hamlin J.L.,
RA Hsueh Y.P., Ianiri G., Jones S., Kodira C.D., Kozubowski L., Lam W.,
RA Marra M., Mesner L.D., Mieczkowski P.A., Moyrand F., Nielsen K., Proux C.,
RA Rossignol T., Schein J.E., Sun S., Wollschlaeger C., Wood I.A., Zeng Q.,
RA Neuveglise C., Newlon C.S., Perfect J.R., Lodge J.K., Idnurm A.,
RA Stajich J.E., Kronstad J.W., Sanyal K., Heitman J., Fraser J.A.,
RA Cuomo C.A., Dietrich F.S.;
RT "Analysis of the genome and transcriptome of Cryptococcus neoformans var.
RT grubii reveals complex RNA expression and microevolution leading to
RT virulence attenuation.";
RL PLoS Genet. 10:E1004261-E1004261(2014).
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DR EMBL; CP003833; AFR98955.2; -; Genomic_DNA.
DR RefSeq; XP_012053639.1; XM_012198249.1.
DR AlphaFoldDB; J9W415; -.
DR GeneID; 23888833; -.
DR KEGG; cng:CNAG_05529; -.
DR VEuPathDB; FungiDB:CNAG_05529; -.
DR OrthoDB; 856430at2759; -.
DR Proteomes; UP000010091; Chromosome 14.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR004274; FCP1_dom.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR PANTHER; PTHR12210; DULLARD PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR12210:SF171; PHOSPHATASE HERZOG; 1.
DR SMART; SM00577; CPDc; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
PE 4: Predicted;
FT DOMAIN 138..326
FT /note="FCP1 homology"
FT /evidence="ECO:0000259|SMART:SM00577"
FT REGION 35..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 86..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..57
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..500
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..536
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 564..578
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 581..600
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..643
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 656 AA; 74502 MW; 786A6B285721B96F CRC64;
MSNPHLKALA ITDLKPFFSL STISHAINMS FRSSHHDGFS GQELEKQPRH TRSGKEWRRY
SPSWPVDFSS PPPDYRSYST SPVRTSRLYH SRSSPSETTR VPWRPPPPPP VSFPPPHYVD
LARPSTKKNK ALVKKTITPK LLVLDLNGAL VWRNRSYRAH MSNPRPYLSC FLEYLFLPET
PSDNENKPSD TRSVRPWEVF VWSSAQPHNV RAMVEGCFGS RWIEGIWEQA SEDGKKGTQN
GEGRLLGVWA RDKMGLKGFE YSRKVQTTKD LRKVLSHLIE TKKLPDPTTP YSEKTIVLLD
DSPLKAIFQP WNQIVIPEFD KALCRSSRLA AGLKSDHYDD YDDGDASTSQ IGQGPEMDKI
LLAVIGILDQ LRHVSNVPLW VRAGGLTFDL DETNLHPPTH ESLPSHVDYQ HWFNDQEVYA
KWVAKGEEAL ERKGIEVRHG LDLLPSPPSR ETQGGVFHAA PIAPLRSPSL DSREEREESY
TRYSPSRPAS CLSPSSSDDH LNLELSEEEV ECTKSESAFA RRKREERARE KSARKVSKGQ
QQFAAYAKPK VDEEAINGKI QPSHMADLLT SGNEAIPSES ESDGKALDEN DIESIAARNK
AKQARRKQSR AERKVKTNGK ERELEELKRE RKEERGSGEA PKKRTLHPRR RRPVKQ
//
