ID J9ZE40_LEPFM Unreviewed; 473 AA.
AC J9ZE40;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Sigma54-specific transcriptional regulator, Fis family {ECO:0000313|EMBL:AFS54148.1};
GN OrderedLocusNames=LFML04_1948 {ECO:0000313|EMBL:AFS54148.1};
OS Leptospirillum ferriphilum (strain ML-04).
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Leptospirillum.
OX NCBI_TaxID=1048260 {ECO:0000313|EMBL:AFS54148.1, ECO:0000313|Proteomes:UP000006177};
RN [1] {ECO:0000313|EMBL:AFS54148.1, ECO:0000313|Proteomes:UP000006177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ML-04 {ECO:0000313|EMBL:AFS54148.1,
RC ECO:0000313|Proteomes:UP000006177};
RX PubMed=22203551; DOI=10.1007/s12275-011-1099-9;
RA Mi S., Song J., Lin J., Che Y., Zheng H., Lin J.;
RT "Complete genome of Leptospirillum ferriphilum ML-04 provides insight into
RT its physiology and environmental adaptation.";
RL J. Microbiol. 49:890-901(2011).
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DR EMBL; CP002919; AFS54148.1; -; Genomic_DNA.
DR RefSeq; WP_014961653.1; NC_018649.1.
DR AlphaFoldDB; J9ZE40; -.
DR STRING; 1048260.LFML04_1948; -.
DR KEGG; lfi:LFML04_1948; -.
DR PATRIC; fig|1048260.3.peg.2117; -.
DR HOGENOM; CLU_000445_8_1_0; -.
DR Proteomes; UP000006177; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR32071:SF95; TRANSCRIPTIONAL REGULATORY PROTEIN ZRAR; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 106..158
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 165..394
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 473 AA; 52509 MW; A2586471AF0FB51A CRC64;
MKSQPVSIRP FPGNLAENGT SSRGLNTFPP GGSPSDAQAI LDSLEEGVVA IGLDKKILYM
NRAAREILKN REDSPTPSDC RKVVNSSECQ ARCVLAKTVE TGEPIRNMEI SLVDALGRRR
VLRLNTALLK DSSGKVFGGV EIFHDISQIV ALKEELKGRY SFGRIIGRSE KMQEIFDLLP
VIAQSKSTVL IEGESGTGKE LVAHALHENS PRREGPFVKL NCAALSEGVL ESELFGHVKG
AFTGAVQSRP GRFELASGGT LFLDEIGEIS PSMQVKLLRV LQEEEFERVG GTKTVKVDVR
VIAATNRDLK QAMEEGSFRK DLYYRLRVIP VTLPPLRERQ GDLPLLIQSF IERYNAELGK
NIQGLTSEAM KVLFNYHYPG NIRELQNIIE HAALLCNDSR IDLRHLPGDL LPVQSQSSFL
ELAMMEENPV RYVEKELIRM AMAESGGNIS EVARKLSMGR STLWRRLKEM KLA
//
