ID K0C5B5_CYCSP Unreviewed; 733 AA.
AC K0C5B5;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Assimilatory nitrate reductase {ECO:0000313|EMBL:AFT66852.1};
GN OrderedLocusNames=Q91_0814 {ECO:0000313|EMBL:AFT66852.1};
OS Cycloclasticus sp. (strain P1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Cycloclasticus.
OX NCBI_TaxID=385025 {ECO:0000313|EMBL:AFT66852.1, ECO:0000313|Proteomes:UP000006282};
RN [1] {ECO:0000313|EMBL:AFT66852.1, ECO:0000313|Proteomes:UP000006282}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P1 {ECO:0000313|EMBL:AFT66852.1,
RC ECO:0000313|Proteomes:UP000006282};
RX PubMed=23144416; DOI=10.1128/JB.01837-12;
RA Lai Q., Li W., Wang B., Yu Z., Shao Z.;
RT "Complete genome sequence of the pyrene-degrading bacterium Cycloclasticus
RT sp. strain P1.";
RL J. Bacteriol. 194:6677-6677(2012).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
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DR EMBL; CP003230; AFT66852.1; -; Genomic_DNA.
DR RefSeq; WP_015005624.1; NC_018697.1.
DR AlphaFoldDB; K0C5B5; -.
DR STRING; 385025.Q91_0814; -.
DR KEGG; cyq:Q91_0814; -.
DR PATRIC; fig|385025.3.peg.830; -.
DR HOGENOM; CLU_000422_13_4_6; -.
DR Proteomes; UP000006282; Chromosome.
DR GO; GO:1990204; C:oxidoreductase complex; IEA:UniProt.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0045333; P:cellular respiration; IEA:UniProt.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd02791; MopB_CT_Nitrate-R-NapA-like; 1.
DR CDD; cd02754; MopB_Nitrate-R-NapA-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR041957; CT_Nitrate-R-NapA-like.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR027467; MopterinOxRdtase_cofactor_BS.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR PIRSF; PIRSF000144; CbbBc; 2.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00551; MOLYBDOPTERIN_PROK_1; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006282}.
FT DOMAIN 19..76
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 733 AA; 82087 MW; 5A74075479BED549 CRC64;
MLFGRNKKNP IAIADKKIEK WTYATCGYCS TGCAIEVGTD KDGVPVGSRG VADADVNRGK
LCVKGLFEHE LFESAGRGDV PLMRSNIHDE YQEASWDESF EKMASEIKRI QDTYGPDSFA
IVSTGQILTE GFYTLGKLAR GVIGTNNYDG NTTLCMASAV SGYKRSFGSD GPPGCYEDFE
HTDCLIAWGS NLPEQHPIIY WRFKEAQEKR KFPLIVIDPR VTMLAQNADM HLAITPGTDV
VLMNSLMHVI LAEGLEDQDY IKANTTGFDE LAAEVKNYDP ITASKICGID EDTIRNVARL
YAKAGAAMNI WTMGINQSTH GSDGVVGLNN LSLLTGNIGK KGGTSLSITG QCNAMGTREW
SSCSGLPGYR LLENEQDRID IGKYWGVDPE FFPKKRGLAQ TDIFPAIETG AIKGLWLVGT
NPMTSMPNTA RIRKTLEKLE CCVVQDSYLD VETTQYAHIF LPAAIWAEKE GVFTNTERRV
NIIRKVKEPY GQSKTDLHIF NGLAKQFEQG RKMNFPDNFH EVFDEMRELS KGRLVDISGM
THDLIEQNKG IQWPYTQEQV DKGEKPLKGG KRLYTEPATF RHPGGRAKLI PLPFIDNNEK
PDEQYPFWLN SGRLVEHFHS RTRTGKVGNN NKYSPTPFME MNPDTAAEQG IEHQSYVRVI
SRRGDAVVMV MLTQRVPRTM VFIPFHFFDC VNRLTLGLLD PHSRQPAFKQ CAVRIEHVNQ
EVAARLNLEA RTF
//
