ID   K0D9Z2_LEUCJ            Unreviewed;       395 AA.
AC   K0D9Z2;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE            EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE   AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN   OrderedLocusNames=C270_03675 {ECO:0000313|EMBL:AFT81648.1};
OS   Leuconostoc carnosum (strain JB16).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Leuconostoc.
OX   NCBI_TaxID=1229758 {ECO:0000313|EMBL:AFT81648.1, ECO:0000313|Proteomes:UP000006299};
RN   [1] {ECO:0000313|EMBL:AFT81648.1, ECO:0000313|Proteomes:UP000006299}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JB16 {ECO:0000313|EMBL:AFT81648.1,
RC   ECO:0000313|Proteomes:UP000006299};
RX   PubMed=23144413; DOI=10.1128/JB.01805-12;
RA   Jung J.Y., Lee S.H., Jeon C.O.;
RT   "Complete genome sequence of Leuconostoc carnosum strain JB16, isolated
RT   from Kimchi.";
RL   J. Bacteriol. 194:6672-6673(2012).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC         ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC         Evidence={ECO:0000256|ARBA:ARBA00000799};
CC   -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC       {ECO:0000256|ARBA:ARBA00005297}.
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DR   EMBL; CP003851; AFT81648.1; -; Genomic_DNA.
DR   RefSeq; WP_014974260.1; NC_018673.1.
DR   AlphaFoldDB; K0D9Z2; -.
DR   STRING; 1229758.C270_03675; -.
DR   GeneID; 61186310; -.
DR   KEGG; lcn:C270_03675; -.
DR   PATRIC; fig|1229758.3.peg.736; -.
DR   eggNOG; COG1169; Bacteria.
DR   HOGENOM; CLU_006493_8_4_9; -.
DR   Proteomes; UP000006299; Chromosome.
DR   GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR   InterPro; IPR005801; ADC_synthase.
DR   InterPro; IPR015890; Chorismate_C.
DR   InterPro; IPR004561; IsoChor_synthase.
DR   NCBIfam; TIGR00543; isochor_syn; 1.
DR   PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR   PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR   Pfam; PF00425; Chorismate_bind; 1.
DR   SUPFAM; SSF56322; ADC synthase; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006299}.
FT   DOMAIN          127..382
FT                   /note="Chorismate-utilising enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00425"
SQ   SEQUENCE   395 AA;  44619 MW;  CD655F1BD98BFD27 CRC64;
     MQYNYTRLVN DKDEQKLYEA LDSFETSAYF RTRDATKARF GFGATVTTDT AELLQDDIAF
     GGRSFDEQKI KNSTLMNGFW FVPRIAVTMT QTTITFSSDE SLDFDTWLAQ IPNMKAEMVH
     VISVDDETDW ADRTEKLIST LKSKQTLKKV VFGRQQILKL SNKLYLSRLI RGLSSQNNTY
     HFILKHQDEF YISATPERLI KVADGHLTTG AVAGTIQRGD NEQDDMALGK LLLASHKNRQ
     EHQYVVENIQ QKLQAMTEKL TVPADPILLK TQQVQHLYTP IIGEIDSQYT LVHLMNQLHP
     TPALGGVPQK EALAYIQDYE RTPRGLFASP MGYLDAEQGG ELVVGIRAMH VNQRSHQATL
     FAGAGIVSDS TAAQEFKETA LKLKAMRQLL KDYSI
//