ID K0HLE0_9BURK Unreviewed; 1630 AA.
AC K0HLE0;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:AFU43788.1};
GN ORFNames=C380_00290 {ECO:0000313|EMBL:AFU43788.1};
OS Acidovorax sp. KKS102.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Acidovorax.
OX NCBI_TaxID=358220 {ECO:0000313|EMBL:AFU43788.1, ECO:0000313|Proteomes:UP000006306};
RN [1] {ECO:0000313|EMBL:AFU43788.1, ECO:0000313|Proteomes:UP000006306}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KKS102 {ECO:0000313|EMBL:AFU43788.1,
RC ECO:0000313|Proteomes:UP000006306};
RX PubMed=23209225; DOI=10.1128/JB.01848-12;
RA Ohtsubo Y., Maruyama F., Mitsui H., Nagata Y., Tsuda M.;
RT "Complete Genome Sequence of Acidovorax sp. Strain KKS102, a
RT Polychlorinated-Biphenyl Degrader.";
RL J. Bacteriol. 194:6970-6971(2012).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003872; AFU43788.1; -; Genomic_DNA.
DR RefSeq; WP_015011883.1; NC_018708.1.
DR STRING; 358220.C380_00290; -.
DR KEGG; ack:C380_00290; -.
DR PATRIC; fig|358220.3.peg.59; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_62_4; -.
DR OrthoDB; 9813903at2; -.
DR Proteomes; UP000006306; Chromosome.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 4.
DR Gene3D; 3.30.450.40; -; 3.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 4.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 4.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 2.
DR Pfam; PF13188; PAS_8; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00065; GAF; 3.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 4.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 4.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 257..309
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 310..382
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 386..438
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 604..675
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1073..1142
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1144..1196
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1228..1366
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 1375..1629
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT COILED 141..180
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1630 AA; 181079 MW; 32D419C94CB3ECE4 CRC64;
MPPAQATAEA ARLQALQSYA ILDTPTEDSF DQLATLAARV CQCPMAVVNF VDSDRQWFKA
AVGVPFKETE RAIAFCAHAL SGSREPMVVN DTHKHPVFAH NPLVTQDPHV RFYACVPLVT
PEGQALGTLA VLDSIPRHIE AEQLEGLRIL AEQAMVQLEL RRQKQVLADL VQQRDKMHAE
LLAQSETLRV AGQMARIGGW IVELPSLQLN WSQEIAAAFG IAGRMGSVEQ IMELYLPPHR
QAMLAAFESC IRHGTPFDLE AELVTLAGRH FWVRTTGQAV RDAEGRIVRI QGAFQDISAQ
HQARQARRES EERFHLVSRA TADAVWDWNL HTDAMWWNEG MQTLFGVPLD QLPPDSTSWT
LRLHPDDSAE VLEGIHAAID GTANHWSDEY RFRRQDGSYA WVLDRGFLIR DLQGKAVRMV
GGMTDISAQK LADLDAQRDA QNHAELLQVQ QRISSLDMPL PEVLQLVAST VLRQTEARGA
MVELLQGRQL VAQASAGDHV RPVGNLLAVD QSLLWPALSK GQTVVCNDTE AEGWDMASMP
HRHGVRSVMA VPLRSGDAIV GSLKVTSDKV NAFSRRDVAH LEILTESLGA MVQLRHVAGQ
LHASEQQYRM LFDEHPHPMW VYDRETLQLQ AVNRSMERHY GYTESELLTM SMLDLWPADR
RPNVEANIRA VPMDQRNKPV ISRHIKKDGS FMDVEITAGS ISFNGRPARQ VLATDVTERL
RTERELARMG RAQRLLSACN ETLVRATSET ALLQAICQIA VDIGGYRMGW VGFAMDDERK
SIRPVAHAGY NQNYLENLHL SWSADDPYGR GPAGIAVRTG RPVIVQDIRT EGDFADWTER
MLEHGFHGVI CLPLREHARD HAQERSFGLL YLYAPDVLQI SPEEAALLQE LSNDLAIGIT
SLRAHKAQQR LQASVLKVAA AVSASTGTEF FVQLVRNMAD ALDAQGGCVV RLLPQSQGQA
PRVVTLAAVL DGQMLPNDEY SLDGTPSLLL MSQRTHVVTD KVQQLYPEAP VLRAVGAQAY
VGQQLCNADG EVVGIVFVLF RHAIADTDFI TSTLQIFASR ASAEIERQLA DIRIRHQASL
LDKAQDAILV RDLDHRIIFW NKSAERLYGW SQLQALGQSI ETLLYEDPTH FRHATQTVLE
QGEWTGEIVQ RHRDGSTIEV EGRWTLVRGD DGQPQSILAI NTDIRQRKAS EREIQRLAFY
DALTGLPNRM LLMDRMHQAL ATAQRRQQGG ALLFIDLDNF KTLNDTLGHD QGDLLLQQVA
QRLNTCVRSV DTVARLGGDE FVVMLEELSP KPHELALHAR GVGEKILAML AVPYALQGYQ
YRSTPSIGIA PFTGEHTTVG ELLKQADLAM YQAKTAGRNT LRFFDPDMQA VVTARAGLET
DLRSALMQEE FLLHFQPQIH QSGRCVGVEA LVRWAHPQRG MVSPAQFIPL AEETGLILPL
GRWVLHTACK LLASWQSDPA LSHLTMAVNV SSRQFRHASF VDDVARVLAI TGAPSAQLKL
ELTESLLVED METTIATMTA LRSYGVGFSL DDFGTGYSSL SYLKRMPLDQ LKIDQSFVRD
LLTDPNDAAI VDTIIGLSRS LGLEVIAEGV ETPEQCALLA RAGCQLYQGY LFSKALSVDV
LDSFLRTSQA
//
