ID K0I7B6_9BURK Unreviewed; 505 AA.
AC K0I7B6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Efflux transporter, rnd family, mfp subunit {ECO:0000313|EMBL:AFU44871.1};
GN ORFNames=C380_05790 {ECO:0000313|EMBL:AFU44871.1};
OS Acidovorax sp. KKS102.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Acidovorax.
OX NCBI_TaxID=358220 {ECO:0000313|EMBL:AFU44871.1, ECO:0000313|Proteomes:UP000006306};
RN [1] {ECO:0000313|EMBL:AFU44871.1, ECO:0000313|Proteomes:UP000006306}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KKS102 {ECO:0000313|EMBL:AFU44871.1,
RC ECO:0000313|Proteomes:UP000006306};
RX PubMed=23209225; DOI=10.1128/JB.01848-12;
RA Ohtsubo Y., Maruyama F., Mitsui H., Nagata Y., Tsuda M.;
RT "Complete Genome Sequence of Acidovorax sp. Strain KKS102, a
RT Polychlorinated-Biphenyl Degrader.";
RL J. Bacteriol. 194:6970-6971(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP003872; AFU44871.1; -; Genomic_DNA.
DR RefSeq; WP_015012948.1; NC_018708.1.
DR AlphaFoldDB; K0I7B6; -.
DR STRING; 358220.C380_05790; -.
DR KEGG; ack:C380_05790; -.
DR PATRIC; fig|358220.3.peg.1182; -.
DR eggNOG; COG0845; Bacteria.
DR eggNOG; COG5569; Bacteria.
DR HOGENOM; CLU_018816_13_1_4; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000006306; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 6.10.140.730; -; 1.
DR Gene3D; 2.40.50.320; Copper binding periplasmic protein CusF; 1.
DR InterPro; IPR021647; CusF_Ec.
DR InterPro; IPR042230; CusF_sf.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR045800; HMBD.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF15; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR Pfam; PF11604; CusF_Ec; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR Pfam; PF19335; HMBD; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
FT DOMAIN 55..82
FT /note="Heavy metal binding"
FT /evidence="ECO:0000259|Pfam:PF19335"
FT DOMAIN 117..322
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 408..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 505 AA; 53661 MW; 5F8646583E501DE2 CRC64;
MTNSVFKKTA VAVALVAAGI ALGWGVSQWR TASSHAVGAS PASTEAAKTD RKVLYWYDPM
SPTQKFDKPG KSPYMDMALV PKYADEDTQE SSGLSVSAQA VQALGLRTAT VEQRDIGSDV
DVLGTVQLND RDVSIVQARS AGFVERVYAR APGDVVAAGA PLADLLLPEW VAAQREFLAV
RALKDESLTT ASRQRLSLLG MPASLVAQVE RTGEPQGRYT VTFPQAGMVA ELMVRQGMTV
SAGASLVRVN GLASVWIEAA VPEAQSGPLQ LGQDAQVRLA AFPGETLKAR IVSILPEANR
DTRTVRVRLE LPNPAQRLKA GMSGQIALAG RTQPALLVPS EAVIRTGKRA LVYVVDGPGK
YHPVQVQLGA EIDDRLVVQG GLTAGQQVVA SAQFLIDSEA SLRGILPAQS QGSSAQPISE
QGPSTSAAPA SKSFTVRGVV DEVTPTELTL THDAVPELKW PGMTMPFKLA SPELATTLKP
EQQVRFTFQQ QGKDFVITAV ERIKP
//
