ID   K0IJX0_NITGG            Unreviewed;       289 AA.
AC   K0IJX0;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Putative prephenate dehydrogenase {ECO:0000313|EMBL:AFU58567.1};
DE            EC=1.3.1.12 {ECO:0000313|EMBL:AFU58567.1};
GN   OrderedLocusNames=Ngar_c16340 {ECO:0000313|EMBL:AFU58567.1};
OS   Nitrososphaera gargensis (strain Ga9.2).
OC   Archaea; Nitrososphaerota; Nitrososphaeria; Nitrososphaerales;
OC   Nitrososphaeraceae; Nitrososphaera.
OX   NCBI_TaxID=1237085 {ECO:0000313|EMBL:AFU58567.1, ECO:0000313|Proteomes:UP000008037};
RN   [1] {ECO:0000313|EMBL:AFU58567.1, ECO:0000313|Proteomes:UP000008037}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ga9.2 {ECO:0000313|Proteomes:UP000008037};
RX   PubMed=23057602; DOI=10.1111/j.1462-2920.2012.02893.x;
RA   Spang A., Poehlein A., Offre P., Zumbragel S., Haider S., Rychlik N.,
RA   Nowka B., Schmeisser C., Lebedeva E.V., Rattei T., Bohm C., Schmid M.,
RA   Galushko A., Hatzenpichler R., Weinmaier T., Daniel R., Schleper C.,
RA   Spieck E., Streit W., Wagner M.;
RT   "The genome of the ammonia-oxidizing Candidatus Nitrososphaera gargensis:
RT   insights into metabolic versatility and environmental adaptations.";
RL   Environ. Microbiol. 14:3122-45(2012).
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DR   EMBL; CP002408; AFU58567.1; -; Genomic_DNA.
DR   AlphaFoldDB; K0IJX0; -.
DR   STRING; 1237085.Ngar_c16340; -.
DR   KEGG; nga:Ngar_c16340; -.
DR   HOGENOM; CLU_036672_1_1_2; -.
DR   InParanoid; K0IJX0; -.
DR   BioCyc; CNIT1237085:G1324-1632-MONOMER; -.
DR   Proteomes; UP000008037; Chromosome.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:AFU58567.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008037}.
FT   DOMAIN          5..279
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   289 AA;  32195 MW;  9DCF9AB0C91705CC CRC64;
     MPKLQEIAIV GAAGKMGSWF TNYFARRGLH VSVYDVNKET LRPSGNVRVA SGISACVKGA
     DLVLVSVPVR MTPQIIRECA KSMKNDGAII SEISSVKHRT FQALRRVPGH LRPLCIHPMF
     GPGASDKMQT KVLLVPVRNE EAELKIVHEM FENAAVKVLP DARTHDKAIA TVLGLTYFAN
     IVFAKVVSGN NISMLKQVSG TTFGLQSLIA ESILTNEPDL VIALIQENPY AKKYIQQYLK
     KAAVVAKMAS ARDSKRLRAD LKKVRSKMQK WQDLQQSYRR MYDIIENMK
//