ID   K0IZ87_AMPXN            Unreviewed;       122 AA.
AC   K0IZ87;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=Cadmium efflux system accessory protein {ECO:0000313|EMBL:BAM46292.1};
GN   Name=cadC {ECO:0000313|EMBL:BAM46292.1};
GN   OrderedLocusNames=AXY_01600 {ECO:0000313|EMBL:BAM46292.1};
OS   Amphibacillus xylanus (strain ATCC 51415 / DSM 6626 / JCM 7361 / LMG 17667
OS   / NBRC 15112 / Ep01).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Amphibacillus.
OX   NCBI_TaxID=698758 {ECO:0000313|EMBL:BAM46292.1, ECO:0000313|Proteomes:UP000006294};
RN   [1] {ECO:0000313|EMBL:BAM46292.1, ECO:0000313|Proteomes:UP000006294}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51415 / DSM 6626 / JCM 7361 / LMG 17667 / NBRC 15112 /
RC   Ep01 {ECO:0000313|Proteomes:UP000006294};
RA   Nakazawa H., Katano Y., Nakamura S., Sasagawa M., Fukada J., Arai T.,
RA   Sasakura N., Mochizuki D., Hosoyama A., Harada K., Horikawa H., Kato Y.,
RA   Harada T., Sasaki K., Sekiguchi M., Hodoyama M., Nishiko R., Narita H.,
RA   Hanamaki A., Hata C., Konno Y., Niimura Y., Yamazaki S., Fujita N.;
RT   "Whole genome sequence of Amphibacillus xylinus NBRC 15112.";
RL   Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AP012050; BAM46292.1; -; Genomic_DNA.
DR   RefSeq; WP_015008898.1; NC_018704.1.
DR   AlphaFoldDB; K0IZ87; -.
DR   STRING; 698758.AXY_01600; -.
DR   KEGG; axl:AXY_01600; -.
DR   PATRIC; fig|698758.3.peg.160; -.
DR   eggNOG; COG0640; Bacteria.
DR   HOGENOM; CLU_097806_7_3_9; -.
DR   OrthoDB; 9794330at2; -.
DR   Proteomes; UP000006294; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:UniProtKB-KW.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR018334; ArsR_HTH.
DR   InterPro; IPR001845; HTH_ArsR_DNA-bd_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; NF033788; HTH_metalloreg; 1.
DR   PANTHER; PTHR43132; ARSENICAL RESISTANCE OPERON REPRESSOR ARSR-RELATED; 1.
DR   PANTHER; PTHR43132:SF6; TRANSCRIPTIONAL REPRESSOR SMTB HOMOLOG; 1.
DR   Pfam; PF01022; HTH_5; 1.
DR   PRINTS; PR00778; HTHARSR.
DR   SMART; SM00418; HTH_ARSR; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00846; HTH_ARSR_1; 1.
DR   PROSITE; PS50987; HTH_ARSR_2; 1.
PE   4: Predicted;
KW   Cadmium resistance {ECO:0000256|ARBA:ARBA00043263};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006294}.
FT   DOMAIN          24..119
FT                   /note="HTH arsR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50987"
SQ   SEQUENCE   122 AA;  13977 MW;  623C8E3C43B6383C CRC64;
     MNNKDACEIY CYDEEKVNRI QRELEKEDIS SVAQLFKAIA EENRAKITFA LLKGEELCVC
     DIANIIDVTV ANASHHLRTL HTQGVVKFRK EGRLAFYSLD DDHVEQLFVN ALKHEKEGKV
     NV
//