ID K0JQ58_SACES Unreviewed; 440 AA.
AC K0JQ58;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN OrderedLocusNames=BN6_03340 {ECO:0000313|EMBL:CCH27666.1};
OS Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC
OS 15066 / NRRL 15764).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1179773 {ECO:0000313|EMBL:CCH27666.1, ECO:0000313|Proteomes:UP000006281};
RN [1] {ECO:0000313|EMBL:CCH27666.1, ECO:0000313|Proteomes:UP000006281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764
RC {ECO:0000313|Proteomes:UP000006281};
RX PubMed=22958348; DOI=10.1186/1471-2164-13-465;
RA Strobel T., Al-Dilaimi A., Blom J., Gessner A., Kalinowski J.,
RA Luzhetska M., Puhler A., Szczepanowski R., Bechthold A., Ruckert C.;
RT "Complete genome sequence of Saccharothrix espanaensis DSM 44229T and
RT comparison to the other completely sequenced Pseudonocardiaceae.";
RL BMC Genomics 13:465-465(2012).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HE804045; CCH27666.1; -; Genomic_DNA.
DR AlphaFoldDB; K0JQ58; -.
DR STRING; 1179773.BN6_03340; -.
DR KEGG; sesp:BN6_03340; -.
DR PATRIC; fig|1179773.3.peg.341; -.
DR eggNOG; COG0470; Bacteria.
DR HOGENOM; CLU_006229_4_1_11; -.
DR BioCyc; SESP1179773:BN6_RS01635-MONOMER; -.
DR Proteomes; UP000006281; Chromosome.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004622; DNA_pol_HolB.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00678; holB; 1.
DR PANTHER; PTHR11669:SF70; POSSIBLE DNA POLYMERASE; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932,
KW ECO:0000313|EMBL:CCH27666.1};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:CCH27666.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006281};
KW Transferase {ECO:0000313|EMBL:CCH27666.1}.
FT REGION 320..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..356
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 440 AA; 46335 MW; 3301F38506FD4C59 CRC64;
MRGRWTRWPG GCAPPCCRCW PGLRRSRWRT TPESSVGLAT VAGKGVWSEV VGQPEAVAVL
GAAAEAAASI VAGGSPPPGA MTHAWLFTGP PGSGRSSTAR AFAAALQCQA ADDRPGCGAC
AGCHTTLAGT HADVRVVAPE GLSIAVAEMR ALVQVSARRP TSGRWQVVII ADADRLTEGA
SNALLKAVEE PPDRTVFLLC APSDHPDDVS VTIRSRCRIV SLGTPRLDAI AAALVEDGVP
ADEANWAASV CGGNVSRARR LATEESVRAR RESVLRIPLA LRRPADIFTC ADNLVQAAEA
DALTANESRD ESERHALETA MGAGGTGKGT AAATRGAKGA LKDLEKRQKS RATRTQRDSL
DQALVDLAAF YRDVLVTSSG ATAVLNHPDR AADARTAARE WTQESTLRRL EAVLACRDAL
ELNVKPRIAV EAMLFTLHRG
//
