ID K0K1G7_SACES Unreviewed; 394 AA.
AC K0K1G7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Glycosyltransferase, family 1 {ECO:0000313|EMBL:CCH34065.1};
DE EC=2.4.1.- {ECO:0000313|EMBL:CCH34065.1};
GN Name=gtuS1-1 {ECO:0000313|EMBL:CCH34065.1};
GN OrderedLocusNames=BN6_68280 {ECO:0000313|EMBL:CCH34065.1};
OS Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC
OS 15066 / NRRL 15764).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1179773 {ECO:0000313|EMBL:CCH34065.1, ECO:0000313|Proteomes:UP000006281};
RN [1] {ECO:0000313|EMBL:CCH34065.1, ECO:0000313|Proteomes:UP000006281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764
RC {ECO:0000313|Proteomes:UP000006281};
RX PubMed=22958348; DOI=10.1186/1471-2164-13-465;
RA Strobel T., Al-Dilaimi A., Blom J., Gessner A., Kalinowski J.,
RA Luzhetska M., Puhler A., Szczepanowski R., Bechthold A., Ruckert C.;
RT "Complete genome sequence of Saccharothrix espanaensis DSM 44229T and
RT comparison to the other completely sequenced Pseudonocardiaceae.";
RL BMC Genomics 13:465-465(2012).
CC -!- PATHWAY: Antibiotic biosynthesis; vancomycin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004660}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 28 family.
CC {ECO:0000256|ARBA:ARBA00006962}.
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DR EMBL; HE804045; CCH34065.1; -; Genomic_DNA.
DR RefSeq; WP_015104176.1; NC_019673.1.
DR AlphaFoldDB; K0K1G7; -.
DR STRING; 1179773.BN6_68280; -.
DR KEGG; sesp:BN6_68280; -.
DR PATRIC; fig|1179773.3.peg.6894; -.
DR eggNOG; COG1819; Bacteria.
DR HOGENOM; CLU_000537_8_0_11; -.
DR OrthoDB; 3253247at2; -.
DR BioCyc; SESP1179773:BN6_RS32930-MONOMER; -.
DR UniPathway; UPA00162; -.
DR Proteomes; UP000006281; Chromosome.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:InterPro.
DR GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0030259; P:lipid glycosylation; IEA:InterPro.
DR GO; GO:0033072; P:vancomycin biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR010610; EryCIII-like_C.
DR InterPro; IPR004276; GlycoTrans_28_N.
DR InterPro; IPR002213; UDP_glucos_trans.
DR PANTHER; PTHR48050; STEROL 3-BETA-GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR48050:SF13; UDP-GLUCURONOSYLTRANSFERASE; 1.
DR Pfam; PF06722; EryCIII-like_C; 1.
DR Pfam; PF03033; Glyco_transf_28; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194};
KW Glycosyltransferase {ECO:0000313|EMBL:CCH34065.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006281};
KW Transferase {ECO:0000313|EMBL:CCH34065.1}.
FT DOMAIN 3..126
FT /note="Glycosyltransferase family 28 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03033"
FT DOMAIN 296..362
FT /note="Erythromycin biosynthesis protein CIII-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF06722"
SQ SEQUENCE 394 AA; 40840 MW; A0351171FDDF9912 CRC64;
MRVVLSTIGS RGEVEPVTGL ALRLRESGAE VRVCAPPDFG DRLTDLGFAF TPVGPEVNGT
ATAPPPTPAQ VREATAETVR AQFEAISEAA RGSDALLGAG GRQIAAHSIA ESLGIHYVYA
AFCAVTLPSP HHPPLIMPEV VVAGEAPPDE ATGNAERWAA DAQRWNSLFA EALNTHRDAR
DLSPVDDVRG HVVTDRPWLA ADQVLGPWPE PGGVFQTGAW TVPDDRPLPA GVEDFLRAGE
PPVYFGFGST PATPELGAAV VAAARAVGRR AIVAGGWAGL TPDEGTLPIG ETNHQALFPR
VAAVVHHGGA GTTAAAARAG VPQVVVPRRY DQPYWARRVV ALGIGTEGTS DSVATALARA
LSPVTVGRAA ALAPEVRTDG TLAATCRLLS LPTT
//
