ID   K0K1R2_SACES            Unreviewed;       918 AA.
AC   K0K1R2;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Putative helicase {ECO:0000313|EMBL:CCH30508.1};
DE            EC=3.6.4.- {ECO:0000313|EMBL:CCH30508.1};
GN   Name=helY {ECO:0000313|EMBL:CCH30508.1};
GN   OrderedLocusNames=BN6_32030 {ECO:0000313|EMBL:CCH30508.1};
OS   Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC
OS   15066 / NRRL 15764).
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharothrix.
OX   NCBI_TaxID=1179773 {ECO:0000313|EMBL:CCH30508.1, ECO:0000313|Proteomes:UP000006281};
RN   [1] {ECO:0000313|EMBL:CCH30508.1, ECO:0000313|Proteomes:UP000006281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764
RC   {ECO:0000313|Proteomes:UP000006281};
RX   PubMed=22958348; DOI=10.1186/1471-2164-13-465;
RA   Strobel T., Al-Dilaimi A., Blom J., Gessner A., Kalinowski J.,
RA   Luzhetska M., Puhler A., Szczepanowski R., Bechthold A., Ruckert C.;
RT   "Complete genome sequence of Saccharothrix espanaensis DSM 44229T and
RT   comparison to the other completely sequenced Pseudonocardiaceae.";
RL   BMC Genomics 13:465-465(2012).
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DR   EMBL; HE804045; CCH30508.1; -; Genomic_DNA.
DR   RefSeq; WP_015100620.1; NC_019673.1.
DR   AlphaFoldDB; K0K1R2; -.
DR   STRING; 1179773.BN6_32030; -.
DR   KEGG; sesp:BN6_32030; -.
DR   PATRIC; fig|1179773.3.peg.3203; -.
DR   eggNOG; COG4581; Bacteria.
DR   HOGENOM; CLU_002902_4_1_11; -.
DR   OrthoDB; 3229913at2; -.
DR   BioCyc; SESP1179773:BN6_RS15585-MONOMER; -.
DR   Proteomes; UP000006281; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CCH30508.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CCH30508.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006281}.
FT   DOMAIN          43..201
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          316..479
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   918 AA;  101385 MW;  52F5FF5E5AED1B56 CRC64;
     MSSASRSPAD AYADFRRRTT RPKLTDFLSV LSFELDPFQQ RACEALEDGH GVLVCAPTGA
     GKTVVGEFAV HLALSEGRKC FYTTPIKALS NQKYADLVAR YGEGKVGLLT GDTSVNGNAP
     VVVMTTEVLR NMLYAGSSTL NSLAYVVMDE VHYLADRFRG PVWEEVILHL PESVRLVGLS
     ATVSNAEEFG EWLVEVRGDT TVVVDEHRPV PLWQHMLAGG RMMDLFAGED AEGATRLNPQ
     LLRHTEDLFR YHVPWSRNKN NKGRPPRGSG FKPPSRVDIV QRLDGAGLLP AIDFVFSRAG
     CDAAVGQCVR AGLRLTAEAE VEVIREIIDS KTRDLPQGDL MVLGYWEWRD ALERGIASHH
     AGLLPAFKET VEELFVRGLV KVVFATETLA LGINMPARTV VLEKLVKYNG EAHVDLTPGE
     YTQLTGRAGR RGIDVEGHAV VVWQPGIDPK AVAGLASTRT YPLRSSFRPG YNMAVNLVNQ
     LGAAAAREIL EQSFAQFQAD RSVVGLARRL DRNREALAGY AEAMSCHLGD FTEYASLRRR
     VADREKALAR QNSSARRAEA ASSLERLRKG DVIAVPSGRR SGLAVVIDPG LEPLGEARPL
     VVTEDRWAGR LSSADFPLPV EVLGHVKLPR QVDTRSPKSR RDLASTLRNT GIVAPSLRKR
     RSTADDDAEL ATLRRALRAH PCHGCEKRED HARWGERYHR LLAETEQLER KVAATTHSLA
     REFDRIRGLL RERGYLHEQE NGPGEEVTEH GKRLTRLYSE SDLLAAECLR HGVWRGLDPG
     ELAAVVSSLV YEARRDGPLE TRLPPGKVDD AMTATARLWA ELEDDERRHK LDRTRQPDPG
     FAWPVYRWAR GESLEKVLSS SEASGTELGA GDFVRWCRQV IDFLDQIRDV VGGGDPVGAT
     ARKAVDALRR GVVAMATV
//