ID K0K2P4_SACES Unreviewed; 518 AA.
AC K0K2P4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Amino acid adenylation domain-containing protein {ECO:0000313|EMBL:CCH30843.1};
GN Name=nrps5-a5 {ECO:0000313|EMBL:CCH30843.1};
GN OrderedLocusNames=BN6_35450 {ECO:0000313|EMBL:CCH30843.1};
OS Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC
OS 15066 / NRRL 15764).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1179773 {ECO:0000313|EMBL:CCH30843.1, ECO:0000313|Proteomes:UP000006281};
RN [1] {ECO:0000313|EMBL:CCH30843.1, ECO:0000313|Proteomes:UP000006281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764
RC {ECO:0000313|Proteomes:UP000006281};
RX PubMed=22958348; DOI=10.1186/1471-2164-13-465;
RA Strobel T., Al-Dilaimi A., Blom J., Gessner A., Kalinowski J.,
RA Luzhetska M., Puhler A., Szczepanowski R., Bechthold A., Ruckert C.;
RT "Complete genome sequence of Saccharothrix espanaensis DSM 44229T and
RT comparison to the other completely sequenced Pseudonocardiaceae.";
RL BMC Genomics 13:465-465(2012).
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DR EMBL; HE804045; CCH30843.1; -; Genomic_DNA.
DR RefSeq; WP_015100955.1; NC_019673.1.
DR AlphaFoldDB; K0K2P4; -.
DR STRING; 1179773.BN6_35450; -.
DR KEGG; sesp:BN6_35450; -.
DR PATRIC; fig|1179773.3.peg.3547; -.
DR eggNOG; COG1020; Bacteria.
DR HOGENOM; CLU_000022_2_12_11; -.
DR OrthoDB; 3243414at2; -.
DR BioCyc; SESP1179773:BN6_RS17185-MONOMER; -.
DR Proteomes; UP000006281; Chromosome.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006281}.
FT DOMAIN 8..362
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 427..498
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 518 AA; 55611 MW; 47728738534E444F CRC64;
MTSLYGWFAD TAARTPDAPA LEVGEDVLTY GVLRDRVDAV ASLVLEANGG RVPGRVALLA
SRSLAAFTGY LAALRLGSVV VPVNPGHPVN RNEVICASAR ADVLLADENG AAQAGVLGAS
AGAVLTLSDD DVRAAVAGEL PDLAVGPDDV AYVLFTSGST GRPKGVPITH GNLAAYVGHN
IERFGIGPGC RVSHTFDLTF DPSVFDLFVT WGGGATLVCP HRTELLTPVD YLVDKAITHW
FSVPSVVSVS ANLGNLPTGR PTVLRQSVFI GEQLTVRQAA LWRAVAPDAR IDNVYGPTEL
TVACTEYRLP DDPDRWPATS NGTIPIGPVY GFLDHVVLDE DGREAADGEL CVRGVQRFVG
YLDPADNPGR FVVRDGDRYV PCTGTEPRPE FYYRTGDRVR WEDGELVHLS RLDHQLKIRG
YRVELGEIEA ALARHDGVTQ AVVVTVPGDD GPDLVAFYTG VEVPDRRFVR WLREYLPIHM
VPRRLHHLPE LPLNPNGKVD RGALRASVLS GAGSSGAN
//
