ID K0K5I0_SACES Unreviewed; 318 AA.
AC K0K5I0;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:CCH35535.1};
GN OrderedLocusNames=BN6_83180 {ECO:0000313|EMBL:CCH35535.1};
OS Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC
OS 15066 / NRRL 15764).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1179773 {ECO:0000313|EMBL:CCH35535.1, ECO:0000313|Proteomes:UP000006281};
RN [1] {ECO:0000313|EMBL:CCH35535.1, ECO:0000313|Proteomes:UP000006281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764
RC {ECO:0000313|Proteomes:UP000006281};
RX PubMed=22958348; DOI=10.1186/1471-2164-13-465;
RA Strobel T., Al-Dilaimi A., Blom J., Gessner A., Kalinowski J.,
RA Luzhetska M., Puhler A., Szczepanowski R., Bechthold A., Ruckert C.;
RT "Complete genome sequence of Saccharothrix espanaensis DSM 44229T and
RT comparison to the other completely sequenced Pseudonocardiaceae.";
RL BMC Genomics 13:465-465(2012).
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DR EMBL; HE804045; CCH35535.1; -; Genomic_DNA.
DR RefSeq; WP_015105642.1; NC_019673.1.
DR AlphaFoldDB; K0K5I0; -.
DR STRING; 1179773.BN6_83180; -.
DR KEGG; sesp:BN6_83180; -.
DR PATRIC; fig|1179773.3.peg.8397; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_1_11; -.
DR BioCyc; SESP1179773:BN6_RS40310-MONOMER; -.
DR Proteomes; UP000006281; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000006281};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..56
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 318 AA; 33864 MW; FAC621F6D6287B69 CRC64;
MVTMKEVAAL AGVSITTVSH VINETRSVAS DTRQRVLKAI DETGYTGDAI ARSLVTGGTK
SLGLAVSLVS HPYFAELIAA IESEATRAGY SLVLIDTRGK AESEQAAVRM LRSRRVDGVL
LTPTSGSAAL PELRRLGVPT VLVDRLTVAQ DLDQVGPENV QATSTLARHL AELGHRRIGL
VTGTPGLATT DERVLGYRLG LGRAGLQWDE DLVAGGLEPL LGRTTAVVVG DHQVLVDVLR
TARARGVRIG TDLALVAYDE VEWAELVDPP LTTMAQPVEE IGRTAVRLLL ARIADPARAP
ETIRLPPALK HRHSCGCH
//
