ID K0K6R7_WICCF Unreviewed; 735 AA.
AC K0K6R7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 13-SEP-2023, entry version 40.
DE RecName: Full=XPG N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BN7_138 {ECO:0000313|EMBL:CCH40605.1};
OS Wickerhamomyces ciferrii (strain ATCC 14091 / BCRC 22168 / CBS 111 / JCM
OS 3599 / NBRC 0793 / NRRL Y-1031 F-60-10) (Yeast) (Pichia ciferrii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Wickerhamomyces.
OX NCBI_TaxID=1206466 {ECO:0000313|EMBL:CCH40605.1, ECO:0000313|Proteomes:UP000009328};
RN [1] {ECO:0000313|EMBL:CCH40605.1, ECO:0000313|Proteomes:UP000009328}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14091 / BCRC 22168 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL
RC Y-1031 F-60-10 {ECO:0000313|Proteomes:UP000009328};
RX PubMed=23193139; DOI=10.1128/EC.00258-12;
RA Schneider J., Andrea H., Blom J., Jaenicke S., Ruckert C., Schorsch C.,
RA Szczepanowski R., Farwick M., Goesmann A., Puhler A., Schaffer S.,
RA Tauch A., Kohler T., Brinkrolf K.;
RT "Draft genome sequence of Wickerhamomyces ciferrii NRRL Y-1031 F-60-10.";
RL Eukaryot. Cell 11:1582-1583(2012).
CC -!- SIMILARITY: Belongs to the XPG/RAD2 endonuclease family.
CC {ECO:0000256|ARBA:ARBA00024023}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH40605.1}.
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DR EMBL; CAIF01000001; CCH40605.1; -; Genomic_DNA.
DR AlphaFoldDB; K0K6R7; -.
DR STRING; 1206466.K0K6R7; -.
DR eggNOG; ENOG502QVHA; Eukaryota.
DR HOGENOM; CLU_378548_0_0_1; -.
DR InParanoid; K0K6R7; -.
DR Proteomes; UP000009328; Unassembled WGS sequence.
DR GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProt.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR CDD; cd09858; PIN_MKT1; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR022039; MKT1_C.
DR InterPro; IPR022040; MKT1_N.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR006086; XPG-I_dom.
DR InterPro; IPR006084; XPG/Rad2.
DR InterPro; IPR006085; XPG_DNA_repair_N.
DR PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11081:SF32; POST-TRANSCRIPTIONAL REGULATOR MKT1; 1.
DR Pfam; PF12246; MKT1_C; 1.
DR Pfam; PF12247; MKT1_N; 1.
DR Pfam; PF00752; XPG_N; 1.
DR SMART; SM00484; XPGI; 1.
DR SMART; SM00485; XPGN; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009328};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT DOMAIN 4..99
FT /note="XPG N-terminal"
FT /evidence="ECO:0000259|SMART:SM00485"
FT DOMAIN 153..222
FT /note="XPG-I"
FT /evidence="ECO:0000259|SMART:SM00484"
SQ SEQUENCE 735 AA; 84393 MW; FCED1EB3398C059B CRC64;
MPIVKSLEQY FFERNLPVTL PVETLKNSRL GIDVNHYLSR LLGSKRELNI DAIGGFPNSL
KTYIRSDVQL FRELNITPIF VFSGNDIVDQ YDLKNSKENS SAETFRERAW NHYGSYQSKN
QTSIPFTPHD TFRDYNAPFT FEAITRDLID YFNDLGLEYF VAPYLSWAQL SYFYETEYID
AIYGPTECVL LPNVDKYIFA FEFPEKVFRF VEKRRLLNEF QIGPQQLLEI AVSVGCDLQP
VTLPIYNGYP QQQLFHIGLS IINGGGNIYS NISALNNEDV KTRFQKGVLA LQYLPVLKQN
GRVELSHYDE HIEPPNPDTL PPSDIHDIIG QRLPHEYFFY ESLGLINPKI LESVVYGTYF
ENQPIDGGIP SQYKSLVSST VNAFKNKELN LLTQSINRYY QVKKIHFVKY FDKDDVELDN
KMYPPMSTTI DGIVIKSDTE TFNFSSFLNS LEEDDLLGKK IIGEYGVSQE ADRLKTDYEI
IATSTLRTLS LLGLIDFKNG KLVPNKWSKS LFAIKNFDPI HQEKLLTLLI FIKLNAFQIT
EPFTPSLIGN STTTDPKNSR TVLLFARLAT FLQVEQKQTQ YIGPISRNIL AFRSSIDLVK
NNIRELLECV LVNSLANNEV SKLDKTNSQW RKLVSQIPYK EGTPNTILGI VFQAVFDIYF
QQDGDLARAK LEVFEAFRGQ HNSISNLEED LSKGFKFIKQ AFNLVEVLHE DNLINSEVFA
DFERVNKITV EALKK
//
