ID K0K9T2_SACES Unreviewed; 546 AA.
AC K0K9T2;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Putative histidine kinase {ECO:0000313|EMBL:CCH34302.1};
GN OrderedLocusNames=BN6_70670 {ECO:0000313|EMBL:CCH34302.1};
OS Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC
OS 15066 / NRRL 15764).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1179773 {ECO:0000313|EMBL:CCH34302.1, ECO:0000313|Proteomes:UP000006281};
RN [1] {ECO:0000313|EMBL:CCH34302.1, ECO:0000313|Proteomes:UP000006281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764
RC {ECO:0000313|Proteomes:UP000006281};
RX PubMed=22958348; DOI=10.1186/1471-2164-13-465;
RA Strobel T., Al-Dilaimi A., Blom J., Gessner A., Kalinowski J.,
RA Luzhetska M., Puhler A., Szczepanowski R., Bechthold A., Ruckert C.;
RT "Complete genome sequence of Saccharothrix espanaensis DSM 44229T and
RT comparison to the other completely sequenced Pseudonocardiaceae.";
RL BMC Genomics 13:465-465(2012).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HE804045; CCH34302.1; -; Genomic_DNA.
DR AlphaFoldDB; K0K9T2; -.
DR STRING; 1179773.BN6_70670; -.
DR KEGG; sesp:BN6_70670; -.
DR PATRIC; fig|1179773.3.peg.7141; -.
DR eggNOG; COG4585; Bacteria.
DR HOGENOM; CLU_000445_20_11_11; -.
DR BioCyc; SESP1179773:BN6_RS34095-MONOMER; -.
DR Proteomes; UP000006281; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CCH34302.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006281};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 41..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..455
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 210..274
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
SQ SEQUENCE 546 AA; 59086 MW; 2454A738433950C3 CRC64;
MSFVTSVVQR LRPEVADIRT APAAFLRTHV ERFRELTPWR VARELVAILA IVLMDVWPGF
IANHDPVSTW WMVVMGIGFV AVYELRLLFP AIALLLGVWV VFSIEHGGVA TILLLAYGSG
YRIVSWQRSL VTAALGLALH MLAWDVNAPG LGGPFGSFVM LTVYGMVVAL PFLVGRYVAQ
RNALVAALHD REETMVRERK VVSRQVRLRE RNRIAQDMHD SLGHRLSLIS VHAGALSLDP
DLGDRHRDAV QVLRSAALTA MEELRGVIGV LRRDEPDEDQ VRRTVDAVDE LVEGARRAGV
RVSLVRGGQP RPLPAKVSHA AYRIAQEGLT NASKHASGAS VQVTVKYEPD ALVVEVRNNP
PRVKAPKGAG FGLIGLGERV RLAGGMLHVG ELPAGGFRIA AVLPYEDTAA AGDEPADDEP
VERVKPTGIR KWAGVGSIAL AGVVVVAVIG GYTWIGSQPT TKVVSPELYD SVRVGDDESA
VRARLPVGAD PLIANVRSAA PAEPEGATCE YFVADDQKYS LRATKVVRFC FAGGKLVEKN
SHQQGT
//
