ID K0KA35_SACES Unreviewed; 958 AA.
AC K0KA35;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=ATP-dependent DNA helicase RecG {ECO:0000256|ARBA:ARBA00017846};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN OrderedLocusNames=BN6_71670 {ECO:0000313|EMBL:CCH34402.1};
OS Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC
OS 15066 / NRRL 15764).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1179773 {ECO:0000313|EMBL:CCH34402.1, ECO:0000313|Proteomes:UP000006281};
RN [1] {ECO:0000313|EMBL:CCH34402.1, ECO:0000313|Proteomes:UP000006281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764
RC {ECO:0000313|Proteomes:UP000006281};
RX PubMed=22958348; DOI=10.1186/1471-2164-13-465;
RA Strobel T., Al-Dilaimi A., Blom J., Gessner A., Kalinowski J.,
RA Luzhetska M., Puhler A., Szczepanowski R., Bechthold A., Ruckert C.;
RT "Complete genome sequence of Saccharothrix espanaensis DSM 44229T and
RT comparison to the other completely sequenced Pseudonocardiaceae.";
RL BMC Genomics 13:465-465(2012).
CC -!- SIMILARITY: Belongs to the helicase family. RecG subfamily.
CC {ECO:0000256|ARBA:ARBA00007504}.
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DR EMBL; HE804045; CCH34402.1; -; Genomic_DNA.
DR RefSeq; WP_015104513.1; NC_019673.1.
DR AlphaFoldDB; K0KA35; -.
DR STRING; 1179773.BN6_71670; -.
DR KEGG; sesp:BN6_71670; -.
DR PATRIC; fig|1179773.3.peg.7243; -.
DR eggNOG; COG1200; Bacteria.
DR HOGENOM; CLU_005122_7_1_11; -.
DR OrthoDB; 9804325at2; -.
DR BioCyc; SESP1179773:BN6_RS34585-MONOMER; -.
DR Proteomes; UP000006281; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd04488; RecG_wedge_OBF; 1.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 1.
DR Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR003587; Hint_dom_N.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047112; RecG/Mfd.
DR InterPro; IPR045562; RecG_dom3_C.
DR InterPro; IPR033454; RecG_wedge.
DR PANTHER; PTHR47964; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47964:SF1; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF19833; RecG_dom3_C; 1.
DR Pfam; PF17191; RecG_wedge; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00306; HintN; 1.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CCH34402.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006281}.
FT DOMAIN 511..685
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 708..885
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 733..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 738..756
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 958 AA; 103684 MW; 1C1C771715688F49 CRC64;
MTTFDEKLVS VLGKKSADAL ESGLGLTTVG ELLRHYPRRY DERGKLTEIK GLELGEHATV
QARVKSARQR RMKSRSGELL EAVITDGSSD LHLVFFGRGS RAVERELLPG REAMFAGKVG
MFNGKLQLAH PDYQVLDAET DGSAAKFAGA FIPVYPAAQG IQSWNVSNCV EQVLALWDGV
AEDPLPADLR EERGLVSLEK ALRDIHRPDG WAAITVAQQR LKWDEAMAVQ LALAQRRRSA
TARPAPACPP RPGLVADAFD ERLPFELTAG QREVGERISA DLSAEQPMNR LLQGEVGSGK
AQPLDALVLT PEGFVAMGDL QVGDQVITQD GSPTEVTGVF PQGEREVFRV VLSDGKSVEC
DLEHLWATHD GEVRTLREIR DDLLRDDPRN HGGAPRWRLP MVVAPDVDCV ELAPVKERHE
LLQGLLSTGG ACDGVDVVFR TESENLADYV SELAESLGGT GVVGYGYEQH EVVVRLPEEF
PPFRDALDRT APPVRYVERV EFVGVKPVQC ISVAHPSRLY VTDHFVVTHN TMVALRAMLQ
VVDAGRQAAM LAPTEVLAAQ HARSLRDLLG DLGQAGELGG AEHATRVTLL TGSMPTAQRK
KALLEIVTGE AGVVVGTHAL IQDKVEFHDL GLVVVDEQHR FGVEQRAALS GRAGGSTPHV
LVMTATPIPR TVAMTVYGDL EVSALRELPQ GRSPISTSVV PMAEKPAWLD RAWQRIREEV
GNGHQVYVVC PRIGDGESEG SSGDEPPKDD TSDRRPPLAV VDVAQRLAEG PLQGLRVDIL
HGRMPPDEKD AVMRAFAGNE VQVLVATTVV EVGVNVPNAT VMVIMDADRF GVSQLHQLRG
RVGRGSAPGL CLLVTEMPDG TATMARLRAV ESTLDGFELA QLDLELRREG DILGAAQSGT
RSGLKMLSLL RDEDVIAEAR IVATQVVDAD PELAAHPGLA SLVAGLLDEE RAEYLEKA
//
