ID K0N2A0_DESTT Unreviewed; 397 AA.
AC K0N2A0;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Lys1: saccharopine dehydrogenase {ECO:0000313|EMBL:CCK78279.1};
DE EC=1.5.1.7 {ECO:0000313|EMBL:CCK78279.1};
GN Name=lys1 {ECO:0000313|EMBL:CCK78279.1};
GN OrderedLocusNames=TOL2_C01090 {ECO:0000313|EMBL:CCK78279.1};
OS Desulfobacula toluolica (strain DSM 7467 / Tol2).
OC Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC Desulfobacteraceae; Desulfobacula.
OX NCBI_TaxID=651182 {ECO:0000313|EMBL:CCK78279.1, ECO:0000313|Proteomes:UP000007347};
RN [1] {ECO:0000313|EMBL:CCK78279.1, ECO:0000313|Proteomes:UP000007347}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7467 / Tol2 {ECO:0000313|Proteomes:UP000007347};
RX PubMed=23088741; DOI=10.1111/j.1462-2920.2012.02885.x;
RA Wohlbrand L., Jacob J.H., Kube M., Mussmann M., Jarling R., Beck A.,
RA Amann R., Wilkes H., Reinhardt R., Rabus R.;
RT "Complete genome, catabolic sub-proteomes and key-metabolites of
RT Desulfobacula toluolica Tol2, a marine, aromatic compound-degrading,
RT sulfate-reducing bacterium.";
RL Environ. Microbiol. 15:1334-55(2013).
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DR EMBL; FO203503; CCK78279.1; -; Genomic_DNA.
DR RefSeq; WP_014955637.1; NC_018645.1.
DR AlphaFoldDB; K0N2A0; -.
DR STRING; 651182.TOL2_C01090; -.
DR KEGG; dto:TOL2_C01090; -.
DR PATRIC; fig|651182.5.peg.131; -.
DR HOGENOM; CLU_032114_0_0_7; -.
DR OrthoDB; 9769367at2; -.
DR Proteomes; UP000007347; Chromosome.
DR GO; GO:0004754; F:saccharopine dehydrogenase (NAD+, L-lysine-forming) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032095; Sacchrp_dh-like_C.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR43796; CARBOXYNORSPERMIDINE SYNTHASE; 1.
DR PANTHER; PTHR43796:SF2; CARBOXYNORSPERMIDINE SYNTHASE; 1.
DR Pfam; PF16653; Sacchrp_dh_C; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:CCK78279.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007347}.
FT DOMAIN 4..137
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
FT DOMAIN 141..389
FT /note="Saccharopine dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16653"
SQ SEQUENCE 397 AA; 44928 MW; 614B78B979B2B515 CRC64;
MSKVLIVGAG GVGSVVAHKC AQVSDVFSQI VLASRTVSKC DAIAGEIEKR FNKKITTAKL
DADNVQETVE LIKSVNPDLV LNVALPYQDL ALMEACLATG VDYLDTANYE PPDLAKFEYK
WQWEYEKRFR EKNLMALLGS GFDPGVTNVF CAWAQKHHFD EIHQLDIIDC NAGDHGQAFA
TNFNPEINIR EITQPGRYWE QGEWVETDPL SWSMNYDFPE GIGPRKCYLM YHEELESLVL
HLKGLKRARF WMTFSDQYLN HLKVLENIGM TRIDPIDFQG EKIIPLQFLK AVLPEPSSLG
PLTKGRTCIG CVMKGIKDNK DKTLYIYNIC SHEEAFKEVG SQAISYTTGV PAMIGAMLML
QKKWHLPGVW NMEQFDPDPF MDALNLHGLP WKVVELS
//
