ID K0NIS0_DESTT Unreviewed; 606 AA.
AC K0NIS0;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=von Willebrand factor, tetratricopeptide domain protein {ECO:0000313|EMBL:CCK79708.1};
GN OrderedLocusNames=TOL2_C15450 {ECO:0000313|EMBL:CCK79708.1};
OS Desulfobacula toluolica (strain DSM 7467 / Tol2).
OC Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC Desulfobacteraceae; Desulfobacula.
OX NCBI_TaxID=651182 {ECO:0000313|EMBL:CCK79708.1, ECO:0000313|Proteomes:UP000007347};
RN [1] {ECO:0000313|EMBL:CCK79708.1, ECO:0000313|Proteomes:UP000007347}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7467 / Tol2 {ECO:0000313|Proteomes:UP000007347};
RX PubMed=23088741; DOI=10.1111/j.1462-2920.2012.02885.x;
RA Wohlbrand L., Jacob J.H., Kube M., Mussmann M., Jarling R., Beck A.,
RA Amann R., Wilkes H., Reinhardt R., Rabus R.;
RT "Complete genome, catabolic sub-proteomes and key-metabolites of
RT Desulfobacula toluolica Tol2, a marine, aromatic compound-degrading,
RT sulfate-reducing bacterium.";
RL Environ. Microbiol. 15:1334-55(2013).
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DR EMBL; FO203503; CCK79708.1; -; Genomic_DNA.
DR RefSeq; WP_014957052.1; NC_018645.1.
DR AlphaFoldDB; K0NIS0; -.
DR STRING; 651182.TOL2_C15450; -.
DR KEGG; dto:TOL2_C15450; -.
DR PATRIC; fig|651182.5.peg.1855; -.
DR HOGENOM; CLU_024570_3_1_7; -.
DR OrthoDB; 9807628at2; -.
DR Proteomes; UP000007347; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR22550:SF5; LEUCINE ZIPPER PROTEIN 4; 1.
DR PANTHER; PTHR22550; SPORE GERMINATION PROTEIN; 1.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF13174; TPR_6; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00028; TPR; 3.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50005; TPR; 2.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007347};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 90..290
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REPEAT 391..424
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 427..460
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 471..606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..512
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..578
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 606 AA; 68257 MW; 387521A6F35A142D CRC64;
MKFAHPYLLN LLWTLIPVFG IMVYGILKRK KILSEFAGAN MFSSIIPGFD PKRRWIKAVL
ILLASGFAIV ALAGPQLGYR WEKTTQKGVD IIIALDCSKS MLAQDIKPNR LERAKREIVD
LLRMMKSDRA GLVAFSGRAI LQCPLTLDHE AFNVFLKVLE PGFLPVGGTN LDAAVTTSYS
GFEKESDTEK AIIIITDGEN TSGDVEETAK EMLKQGIKIF CIGVGDLQGA PIPDENGGFK
KDASGNIVLS RVDEQGLEKL AAMTGGAYVR SVAGDMDLDV IYKDKILGTM ERKTLTSGKK
KVWENRYQWF LFPCLVLLLM EFVLSSKRKS HRWFVVIVAF SLSLFSAQTV PVYAKTVSSS
VKQGIQAYEE QKYEQAKKHF IDAQLERPDN ETLYYNIGAA AYMNKEYEHA LKNFTEAARS
EDVNLRHNAQ YNLANTQYQM GNFNEAIKGY EAVLKKFPDD NDAKENLALA KQKKQEQEQQ
KSNPDKDGDD KNKDKQNNQD KQNTEGLDKN QEQEKNQNQN QNKNQNQQQD KPSSEHQQGD
NPGETPSQAQ DKKTQQAKGN ETAASEDNQQ QKQADQAMEN MLNRLEDKPG SAMMPVIEER
HIEKDW
//
