ID K0NKX9_DESTT Unreviewed; 585 AA.
AC K0NKX9;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Conserved uncharacterized membrane protein {ECO:0000313|EMBL:CCK82236.1};
GN OrderedLocusNames=TOL2_C40800 {ECO:0000313|EMBL:CCK82236.1};
OS Desulfobacula toluolica (strain DSM 7467 / Tol2).
OC Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC Desulfobacteraceae; Desulfobacula.
OX NCBI_TaxID=651182 {ECO:0000313|EMBL:CCK82236.1, ECO:0000313|Proteomes:UP000007347};
RN [1] {ECO:0000313|EMBL:CCK82236.1, ECO:0000313|Proteomes:UP000007347}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7467 / Tol2 {ECO:0000313|Proteomes:UP000007347};
RX PubMed=23088741; DOI=10.1111/j.1462-2920.2012.02885.x;
RA Wohlbrand L., Jacob J.H., Kube M., Mussmann M., Jarling R., Beck A.,
RA Amann R., Wilkes H., Reinhardt R., Rabus R.;
RT "Complete genome, catabolic sub-proteomes and key-metabolites of
RT Desulfobacula toluolica Tol2, a marine, aromatic compound-degrading,
RT sulfate-reducing bacterium.";
RL Environ. Microbiol. 15:1334-55(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TVP38/TMEM64 family.
CC {ECO:0000256|ARBA:ARBA00008640}.
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DR EMBL; FO203503; CCK82236.1; -; Genomic_DNA.
DR AlphaFoldDB; K0NKX9; -.
DR STRING; 651182.TOL2_C40800; -.
DR KEGG; dto:TOL2_C40800; -.
DR HOGENOM; CLU_018812_0_0_7; -.
DR Proteomes; UP000007347; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR004017; Cys_rich_dom.
DR InterPro; IPR015414; TMEM64.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR12677:SF59; TVP38_TMEM64 FAMILY INNER MEMBRANE PROTEIN YDJZ; 1.
DR PANTHER; PTHR12677; UNCHARACTERIZED; 1.
DR Pfam; PF02754; CCG; 2.
DR Pfam; PF13534; Fer4_17; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007347};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 372..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 556..577
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 112..191
FT /note="Cysteine-rich"
FT /evidence="ECO:0000259|Pfam:PF02754"
FT DOMAIN 222..302
FT /note="Cysteine-rich"
FT /evidence="ECO:0000259|Pfam:PF02754"
FT DOMAIN 429..544
FT /note="VTT"
FT /evidence="ECO:0000259|Pfam:PF09335"
SQ SEQUENCE 585 AA; 65665 MW; 569B45710A5FB4CF CRC64;
MKNLAMKCTG CDVCVKECSF LQYYGNPGKI AADFYAGRAN ELISFECSLC GLCSSLCPKH
IDPYKVFFQM RNAVWTQTKE IMPEHKAILA YEKKGLSKRY SLYKLPDACT TVFFPGCTFT
GTRTKRTEQI YSWLKNKIPC IGIVLDCCAK PSHDLGRDDF FNTNFLALER FLYDNGVKTV
ITACPNCYTV FSTYSKKLKT KSIYEILAKQ ERTATNKLIG CVTVHDPCVT RFETDMHNYV
RKLLTDNGLE IKEMKHCREK TVCCGEGGSV LFVAPDFASN WGNTRKKEAA DKRIITYCAG
CCSLLGKTVQ TDHVLDLLFE PEKTMQGSVK PSSAPFTYFH RLNLKRKLKK QTKHDVMEKV
YFPIEHQRMT KIFKVLIMVI LAAGVAGIKM TGAEEIFNQE AIQTYINGFG SLAPLVYMII
VAFSPVFFLP GTPFIIAGGL IFGPFQGVVY GITGATSGAC LAFLVSRYVA SEWIESKLTN
PSWLKLKRQT EKHGWKIVAI TRLVPLVPFN LLSYALGLTR IKFTTYFITS FICMLPGCIG
YILLSGSVLE VLQGKLSIKF FAGLGIIILL SLIPVFFKKI KPEDL
//
