ID K0NLP9_DESTT Unreviewed; 404 AA.
AC K0NLP9;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=CBS domain protein {ECO:0000313|EMBL:CCK80953.1};
GN OrderedLocusNames=TOL2_C27930 {ECO:0000313|EMBL:CCK80953.1};
OS Desulfobacula toluolica (strain DSM 7467 / Tol2).
OC Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC Desulfobacteraceae; Desulfobacula.
OX NCBI_TaxID=651182 {ECO:0000313|EMBL:CCK80953.1, ECO:0000313|Proteomes:UP000007347};
RN [1] {ECO:0000313|EMBL:CCK80953.1, ECO:0000313|Proteomes:UP000007347}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7467 / Tol2 {ECO:0000313|Proteomes:UP000007347};
RX PubMed=23088741; DOI=10.1111/j.1462-2920.2012.02885.x;
RA Wohlbrand L., Jacob J.H., Kube M., Mussmann M., Jarling R., Beck A.,
RA Amann R., Wilkes H., Reinhardt R., Rabus R.;
RT "Complete genome, catabolic sub-proteomes and key-metabolites of
RT Desulfobacula toluolica Tol2, a marine, aromatic compound-degrading,
RT sulfate-reducing bacterium.";
RL Environ. Microbiol. 15:1334-55(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FO203503; CCK80953.1; -; Genomic_DNA.
DR AlphaFoldDB; K0NLP9; -.
DR STRING; 651182.TOL2_C27930; -.
DR KEGG; dto:TOL2_C27930; -.
DR PATRIC; fig|651182.5.peg.3310; -.
DR HOGENOM; CLU_015237_4_1_7; -.
DR OrthoDB; 9798188at2; -.
DR Proteomes; UP000007347; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF4; UPF0053 PROTEIN SLL1254; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000007347};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 47..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 40..224
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 307..365
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 404 AA; 45452 MW; 4CEAEAD9C0E999C0 CRC64;
MKLSLKWSSW IFALVLSLVL AFSADVFGLK DSYERSIEYM SADGLLLIIY VLIALIISFL
CSVAESVLLS ITPSYIEGQK KRRPKHAALL KRLRRDNVDQ SLAAILTLNT IAHTVGAIGA
GAKATIVFGS TWFGLFSVIM TLLILFFSEI VPKTLGTIYW SKLASPILYF VNTLIVILYP
IVWISERLTN FISHGKDINI FSREEFIAMA QVGVETGHIL DKESKIIRNI FRFESLKTND
IMTPRVVISA LPEDMKIIDS LKEVIQTPFS RLPLYSTNID DITGFVLKED ILINAAQKRG
NEKIKALKRE IIAVPKSVSL IALLERFLKD RQHIAIVVNE YGGTDGVVTL EDLIETLTGM
EIMDETDDVE DMRALARKQW KERTKAMGLD ADIFDQSKAE KMKD
//
