ID K0NRV7_DESTT Unreviewed; 355 AA.
AC K0NRV7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=NeuB: N-acetylneuraminate synthase {ECO:0000313|EMBL:CCK81697.1};
DE EC=2.5.1.56 {ECO:0000313|EMBL:CCK81697.1};
GN Name=neuB {ECO:0000313|EMBL:CCK81697.1};
GN OrderedLocusNames=TOL2_C35400 {ECO:0000313|EMBL:CCK81697.1};
OS Desulfobacula toluolica (strain DSM 7467 / Tol2).
OC Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC Desulfobacteraceae; Desulfobacula.
OX NCBI_TaxID=651182 {ECO:0000313|EMBL:CCK81697.1, ECO:0000313|Proteomes:UP000007347};
RN [1] {ECO:0000313|EMBL:CCK81697.1, ECO:0000313|Proteomes:UP000007347}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7467 / Tol2 {ECO:0000313|Proteomes:UP000007347};
RX PubMed=23088741; DOI=10.1111/j.1462-2920.2012.02885.x;
RA Wohlbrand L., Jacob J.H., Kube M., Mussmann M., Jarling R., Beck A.,
RA Amann R., Wilkes H., Reinhardt R., Rabus R.;
RT "Complete genome, catabolic sub-proteomes and key-metabolites of
RT Desulfobacula toluolica Tol2, a marine, aromatic compound-degrading,
RT sulfate-reducing bacterium.";
RL Environ. Microbiol. 15:1334-55(2013).
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DR EMBL; FO203503; CCK81697.1; -; Genomic_DNA.
DR RefSeq; WP_014958885.1; NC_018645.1.
DR AlphaFoldDB; K0NRV7; -.
DR STRING; 651182.TOL2_C35400; -.
DR KEGG; dto:TOL2_C35400; -.
DR PATRIC; fig|651182.5.peg.4163; -.
DR HOGENOM; CLU_040465_0_0_7; -.
DR OrthoDB; 9781701at2; -.
DR Proteomes; UP000007347; Chromosome.
DR GO; GO:0050462; F:N-acetylneuraminate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR CDD; cd11615; SAF_NeuB_like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR InterPro; IPR006190; AFP_Neu5c_C.
DR InterPro; IPR036732; AFP_Neu5c_C_sf.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR020007; N-AcNeuraminate_synthase.
DR InterPro; IPR013132; Neu5Ac_N.
DR InterPro; IPR013974; SAF.
DR NCBIfam; TIGR03569; NeuB_NnaB; 1.
DR PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR Pfam; PF03102; NeuB; 1.
DR Pfam; PF08666; SAF; 1.
DR SMART; SM00858; SAF; 1.
DR SUPFAM; SSF51269; AFP III-like domain; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50844; AFP_LIKE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007347};
KW Transferase {ECO:0000313|EMBL:CCK81697.1}.
FT DOMAIN 295..353
FT /note="AFP-like"
FT /evidence="ECO:0000259|PROSITE:PS50844"
SQ SEQUENCE 355 AA; 39310 MW; 7D778E0060E1C759 CRC64;
MNDFVRIKDF KIGINHPCLI IAEAGVNHNG DINIAHKLIE AAKLAGADAV KFQSFKAESL
VTKYSKKADY QLKTTNGDNS QFSMLKKLEL SKQDQAQLKK HCDDENILYL CTPYEQNSAD
LLENIGVDAY KIASTDTSNV PFLRYLAKKE IPVILSTGMS NLGDIEESVN ELKFHGLNGK
IIILQCTSEY PAPLEDINLR AMKTMQLAFG CPVGFSDHTS GIGASPWAVA AGACVVEKHF
TLDRNMKGPD HKASVETKEM AQLVRVIRNV ELALGDGMKR IMPSERKNKS KMQKSLVANR
EISAGRMIRP EDLTCKRPGT GLPPNWFDRV IGTQAAKTIN KDDVLNLDSI SWKTE
//
