ID   K0P1V5_9BACT            Unreviewed;       690 AA.
AC   K0P1V5;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=HD-GYP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CAHE_0117 {ECO:0000313|EMBL:CCM09899.1};
OS   Cardinium endosymbiont cEper1 of Encarsia pergandiella.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Amoebophilaceae;
OC   Cardinium.
OX   NCBI_TaxID=1231626 {ECO:0000313|EMBL:CCM09899.1, ECO:0000313|Proteomes:UP000003996};
RN   [1] {ECO:0000313|EMBL:CCM09899.1, ECO:0000313|Proteomes:UP000003996}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Zchori-Fein et al. 2004 {ECO:0000313|Proteomes:UP000003996};
RX   PubMed=23133394; DOI=10.1371/journal.pgen.1003012;
RA   Penz T., Schmitz-Esser S., Kelly S.E., Cass B.N., Muller A., Woyke T.,
RA   Malfatti S.A., Hunter M.S., Horn M.;
RT   "Comparative Genomics Suggests an Independent Origin of Cytoplasmic
RT   Incompatibility in Cardinium hertigii.";
RL   PLoS Genet. 8:e1003012-e1003012(2012).
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DR   EMBL; HE983995; CCM09899.1; -; Genomic_DNA.
DR   AlphaFoldDB; K0P1V5; -.
DR   STRING; 1231626.CAHE_0117; -.
DR   KEGG; che:CAHE_0117; -.
DR   eggNOG; COG0317; Bacteria.
DR   HOGENOM; CLU_009319_0_0_10; -.
DR   Proteomes; UP000003996; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   Pfam; PF13328; HD_4; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        43..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        70..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        101..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        140..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        176..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   690 AA;  79437 MW;  DDDE74F4B712CC20 CRC64;
     MSHVTFIIFL MLPFQLLLLI FIIGSFCLLD ASYLKKKLMK LEPCNTVIGY TGCYVIITTA
     ILSYVGQCLV YWYILQIAAG IWLIGYSVVS HNRVPSWQIS RSWLIGAMFC LPINVLWHWW
     HVTDYLFLLK LSLAHLSVAL FVFPLSLGMI VLAVTFSAIV YVSCYVENLI ELTDDIVVLF
     GFSTLVFTMI IYCKVQIADY TAHKRYLKDK KKIEREKNYT LKLKQTIHNL HIRAKKPYSK
     RDSNFLDKIV KIVMESPLFL EDDTLYKEDF NIIVNKFFTW SIFLKEHTKS KFHLRLLPTE
     IRLKELIQEL ETGLNDSVES APQLSIVQGD VDMTTKIVCD VNQIIHLLVA VILRITHLEQ
     SASIRIQLHT TRLKYQKYNP IKKQKPPEIV FPAIALVVNS GNIPLSKFAS IKSYYQDITE
     GIELIGALNQ SSSEQINIQK EPIERNIRAH YGYLQFSPSK QKTILLVLPC NVKVVQDAML
     TNLAPSNSYV NKSEINTSME VLMKFNDYAC KMCNIRIGVM DEIFLLLRRC YAFRRHASGK
     LFYVRAIGIA RLVTDWVNYA PEPIYAALLY DLVVYTDLPI SYIKANYSLA IFSFVQSIIS
     IQNRKDLEPS GLSIDNQRKK IVNQDQLFIL CIKLAERLYD LRQAYGYTHK VHVSNMAKET
     LTVDVCLAKK YLDNDIVEAL QRAAQDALRI
//