ID   K0P8R5_9BACT            Unreviewed;       265 AA.
AC   K0P8R5;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Bifunctional protein BirA {ECO:0000313|EMBL:CCM09865.1};
DE            EC=6.3.4.15 {ECO:0000313|EMBL:CCM09865.1};
GN   Name=birA {ECO:0000313|EMBL:CCM09865.1};
GN   ORFNames=CAHE_0083 {ECO:0000313|EMBL:CCM09865.1};
OS   Cardinium endosymbiont cEper1 of Encarsia pergandiella.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Amoebophilaceae;
OC   Cardinium.
OX   NCBI_TaxID=1231626 {ECO:0000313|EMBL:CCM09865.1, ECO:0000313|Proteomes:UP000003996};
RN   [1] {ECO:0000313|EMBL:CCM09865.1, ECO:0000313|Proteomes:UP000003996}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Zchori-Fein et al. 2004 {ECO:0000313|Proteomes:UP000003996};
RX   PubMed=23133394; DOI=10.1371/journal.pgen.1003012;
RA   Penz T., Schmitz-Esser S., Kelly S.E., Cass B.N., Muller A., Woyke T.,
RA   Malfatti S.A., Hunter M.S., Horn M.;
RT   "Comparative Genomics Suggests an Independent Origin of Cytoplasmic
RT   Incompatibility in Cardinium hertigii.";
RL   PLoS Genet. 8:e1003012-e1003012(2012).
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DR   EMBL; HE983995; CCM09865.1; -; Genomic_DNA.
DR   RefSeq; WP_014934239.1; NC_018605.1.
DR   AlphaFoldDB; K0P8R5; -.
DR   STRING; 1231626.CAHE_0083; -.
DR   KEGG; che:CAHE_0083; -.
DR   PATRIC; fig|1231626.3.peg.83; -.
DR   eggNOG; COG0340; Bacteria.
DR   HOGENOM; CLU_051096_3_1_10; -.
DR   OrthoDB; 9807064at2; -.
DR   BioCyc; CEND1231626:AL022_RS00385-MONOMER; -.
DR   Proteomes; UP000003996; Chromosome.
DR   GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   CDD; cd16442; BPL; 1.
DR   InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR   InterPro; IPR004408; Biotin_CoA_COase_ligase.
DR   InterPro; IPR004143; BPL_LPL_catalytic.
DR   NCBIfam; TIGR00121; birA_ligase; 1.
DR   PANTHER; PTHR12835; BIOTIN PROTEIN LIGASE; 1.
DR   PANTHER; PTHR12835:SF5; BIOTIN--PROTEIN LIGASE; 1.
DR   Pfam; PF03099; BPL_LplA_LipB; 1.
DR   SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR   PROSITE; PS51733; BPL_LPL_CATALYTIC; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:CCM09865.1}.
FT   DOMAIN          30..201
FT                   /note="BPL/LPL catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS51733"
SQ   SEQUENCE   265 AA;  29865 MW;  CA8E48C7EB81F445 CRC64;
     MDINHISMND LFNPLSSAIQ TDALFDRASF YYESCASTND LAQTYLLHAA EGTVFIADYQ
     YQGRGQRGSK WTSESGKNIL FSFIIYPEWL TIDGVFALNV ITSLAIYDAL VDHLPKGMAI
     KWPNDLYYLD KKLGGILIET NIGDGHKIKA AVIGIGLNVN QLHFESANFT SLAIHKGNSF
     DRALLLTHIM DAFGSYYAHL QNGINNLLWE KYVNRLYRKT GFHIFATRNG WIERCILSVN
     RAGELVVAGR DGTQYCYKPK EIAFI
//